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nephrosis/phosphatase
Link salvestatakse lõikelauale
Leht 1 alates 28 tulemused
GLEPP1 receptor tyrosine phosphatase (Ptpro) in rat PAN nephrosis. A marker of acute podocyte injury.
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Logi sisse
Glomerular epithelial protein 1 (GLEPP1) is a podocyte receptor membrane protein tyrosine phosphatase located on the apical cell membrane of visceral glomerular epithelial cell and foot processes. This receptor plays a role in regulating the structure and function of podocyte foot process. To better
[Modifications of the enzymatic activity in experimental nephrosis due to antirenal serum. I. Histochemical picture of acid and alkaline phosphatases and of lipases in the kidneys].
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Logi sisse
Thrombosis of the vena cava and hepatic veins (Chiari's syndrome) in a patient with nephrosis; report of a case and observation on serum phosphatase and prothrombin time of plasma.
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The use of urinary N-acetyl-beta-D-glucosaminidase (NAG) for the detection of contrast-media-induced 'osmotic nephrosis' in rats.
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Logi sisse
Excretion of urinary N-acetyl-beta-glucosaminidase (NAG), lactate dehydrogenase (LDH), alkaline phosphatase (ALP) and gamma-glutamyltransferase (gamma-GT) was studied following single intravenous administrations of a non-ionic monomeric contrast medium (iohexol) at doses of 5.0, 7.5, 10.0 and 12.5 g
Glomerular lysosomal enzymes in aminonucleoside nephrosis.
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Logi sisse
Lysosomal hydrolases produce degradation of glomerular basement membrane and may play a key role in catabolism of glycoproteins of extracellular matrix in glomeruli. Therefore we investigated activities of some lysosomal enzymes and stability of lysosomes in glomeruli of normal and nephrotic rats.
Activities of lysosomal enzymes in isolated glomeruli. Alterations in experimental nephrosis.
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Logi sisse
To study the role of lysosomal enzymes in glomeruli, we examined specific activities of lysosomal hydrolases in isolated glomeruli and, for comparison in isolated tubules, from rat kidney cortex of normal animals and animals with puromycin aminonucleoside nephrosis (PAN). Nephrotic syndrome was
Podocyte Protein, Nephrin, Is a Substrate of Protein Tyrosine Phosphatase 1B.
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Logi sisse
Glomerular podocytes are critical for the barrier function of the glomerulus in the kidney and their dysfunction causes protein leakage into the urine (proteinuria). Nephrin is a key podocyte protein, which regulates the actin cytoskeleton via tyrosine phosphorylation of its cytoplasmic domain. Here
Cyclodextrin nephrosis in the rat.
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Logi sisse
The renal toxicity of the Schardinger dextrins, alpha and beta-cyclodextrin, is manifested as a series of alterations in the vacuolar organelles of the proximal convoluted tubule. These changes begin as an increase of apical vacuoles and the appearance of giant lysosomes. The giant lysosomes
Probable toxicosis in cattle in Israel caused by the oak Quercus calliprinos.
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Logi sisse
A probable outbreak of oak (Quercus calliprinos) toxicosis in a herd of beef cattle--heifers and first-calving cows--grazing in the Judean foothills of Israel is described. Toxicosis probably occurred because of the consumption of oak leaves and buds during a period of pasture scarcity without any
Effects of a dietary load of acid or base on changes induced by lactose in rats.
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Logi sisse
Feeding lactose or other slowly digestible carbohydrates to adult mammals may induce a variety of effects including hyperplasia and neoplasia. The most fundamental effect probably is the increased production in the large intestine of short-chain fatty acids (SCFA) resulting from increased
[Structural and metabolic disorders in the heart, liver and kidneys in adjuvant disease].
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Logi sisse
Histochemical changes in the heart, liver and kidneys and ultrastructural disorders in cardiomyocytes were studied in 40 white rats with adjuvant disease. Mucoid lesions, hydropyc dystrophy and necribiosis of muscle cells developed in the heart, diffuse extra-intracapillary glomerulonephritis in
Chronic toxicity and carcinogenicity of bis(tri-n-butyltin)oxide (TBTO) in the rat.
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Logi sisse
In a 106-wk toxicity and carcinogenicity study, groups of 60 male and 60 female weanling Wistar rats were fed 0, 0.5, or 50 mg bis(tri-n-butyltin)oxide (TBTO)/kg diet. In males, feed consumption was increased in all treated groups and increased water consumption occurred at 5 and 50 mg/kg. During
Hepatotoxicity and renal toxicity in rats of corn samples associated with field cases of equine leukoencephalomalacia.
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Logi sisse
Currently there is no convenient bioassay to determine the potential toxicity of corn naturally contaminated with Fusarium moniliforme. A short-term bioassay would be useful for future investigations aimed at isolating as yet unidentified toxins produced by this fungus. Two groups of five male
A preliminary investigation on renal and hepatic toxicity in rats fed purified fumonisin B1.
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Logi sisse
Fumonisins are metabolites of Fusarium moniliforme and other Fusarium spp. Fumonisin B1 (FB1) was hepatocarcinogenic (50 ppm, > or = 90% purity) when fed to male rats; however, neither the effects of FB1 on females nor the relationship between dietary FB1 levels and toxicity in rats has been
Toxicity of chloroform extract of prunus africana stem bark in rats: gross and histological lesions.
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Logi sisse
Chloroform extract of Prunus africana (Hook f. (Rosaceae) did not cause clinical signs or pathology in rats at daily oral doses of up to 1,000 mg/kg for 8 weeks. The extract caused marked clinical signs, organ damage and a 50% mortality rate at a dose of 3.3 g/kg for 6 days. The main lesions
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