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neuralgia/põletik

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Leht 1 alates 263 tulemused
BACKGROUND OF THE INVENTION 1. Field of the Invention This invention relates to nitrone compounds and their use as therapeutic agents for the treatment of inflammation-related conditions and neuropathic pain in mammals, including humans. 2. State of the Art Arthritis and related inflammatory disease

Methods of treating inflammation or neuropathic pain

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BACKGROUND Monoacylglycerol lipase (MGLL or MAGL) is an enzyme responsible for hydrolyzing endocannabinoids such as 2-AG (2-arachidonoylglycerol), an arachidonate based lipid, in the nervous system. SUMMARY OF THE INVENTION Disclosed herein are methods of treating inflammation or neuropathic pain in

Method of treating neuropathic pain

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FIELD OF THE INVENTION The invention relates to bis-quaternary ammonium salts and their use as agents for pain modulation, treatment, reversal and/or prevention of inflammatory pain, neuropathic pain or nociceptive pain. BACKGROUND OF THE INVENTION The treatment of pain is a critical health issue.

Vitamin D3 for the transdermal treatment of pain and inflammation

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FIELD OF THE INVENTION The present invention relates to a medicament for the relief of pain and inflammation, in particular neurogenic inflammation and neuropathic pain. The medicament of the present invention has been found to be especially effective in the relief of peripheral neuropathic
The present invention relates to the treatment or prophylaxis of pain and provides a method of treating or preventing pain as well as the use of certain compounds in the manufacture of medicaments for the treatment or prophylaxis of pain in humans and non-human animals. Pain is a multifaceted or
This application is a U.S. national stage application, filed under 35 U.S.C. 371, of International Application PCT/IB2009/000448, filed Mar. 6, 2009, which claims priority under 35 U.S.C. 120 to Great Britain Application No. 0804213.7, filed Mar. 6, 2008. The present invention relates to the

Benzoic acid and benzoic acid ester derivatives to treat inflammation

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BACKGROUND OF THE PRESENT INVENTION The present invention is novel compounds, which are derivatives of benzoic acid and benzoic acid esters--having antiinflammatory activity for the treatment of arthritis, asthma, Raynaud's disease, inflammatory bowel disorders, trigeminal or herpetic neuralgia,
BACKGROUND OF THE PRESENT INVENTION The present invention is novel compounds, which are derivatives of hydroxybenzylamine and as such are related to capsaicin. The present compounds have antiinflammatory activity for the treatment of arthritis, asthma, Raynaud's disease, inflammatory bowel
CROSS-REFERENCE TO RELATED APPLICATIONS This application is a 371 of PCT/KR2010/007845, filed Nov. 8, 2010, which claims the benefit of Korean Patent Application No. 10-2009-0106912, filed Nov. 6, 2009, the entire contents of each of which are incorporated herein by reference. TECHNICAL FIELD The

Use of isoQC inhibitors in the treatment and prevention of inflammatory diseases or conditions

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INCORPORATION-BY-REFERENCE OF SEQUENCE LISTING The Sequence Listing, which is a part of the present disclosure, includes a computer readable form comprising nucleotide and/or amino acid sequences of the present invention. The subject matter of the Sequence Listing is incorporated herein by reference

Benzoic acid and benzoic acid ester derivatives having anti-inflammatory and analgesic activity

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BACKGROUND OF THE PRESENT INVENTION The present invention is novel compounds, which are derivatives of benzoic acid and benzoic acid esters--having antiinflammatory activity for the treatment of arthritis, asthma, Raynaud's disease, inflammatory bowel disorders, trigeminal or herpetic neuralgia,

Benzoic acid and benzoic acid ester derivatives having anti-inflammatory and analgesic activity

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BACKGROUND OF THE PRESENT INVENTION The present invention is novel compounds, which are derivatives of benzoic acid and benzoic acid ester--having antiinflammatory activity for the treatment of arthritis, asthma, Raynaud's disease, inflammatory bowel disorders, trigeminal or herpetic neuralgia,

6-1H-imidazo-quinazoline and quinolines derivatives, new potent analgesics and anti-inflammatory agents

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The present invention is directed to novel 6-1H-imidazo-2-aryl and 2-heteroaryl quinazoline and quinolines, to a process for their preparation, to their pharmaceutical compositions and to the use of such compounds and their pharmaceutical compositions for the treatment of pain and inflammatory

6-1H-imidazo-quinazoline and quinolines derivatives, new potent analgesics and anti-inflammatory agents

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The present invention is directed to novel 6-1H-imidazo-2-aryl and 2-heteroaryl quinazoline and quinolines, to a process for their preparation, to their pharmaceutical compositions and to the use of such compounds and their pharmaceutical compositions for the treatment of pain and inflammatory
The present invention is directed to novel amidines of 2-heteroaryl-quinazoline and quinolines, to a process for their preparation, to their pharmaceutical compositions and to the use of such compounds and their pharmaceutical compositions for the treatment of pain and inflammatory related
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