neurogenic inflammation/lauk

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TRPA1 Channel as a Regulator of Neurogenic Inflammation and Pain: Structure, Function, Role in Pathophysiology, and Therapeutic Potential of Ligands.

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Logi sisse

TRPA1 is a cation channel located on the plasma membrane of many types of human and animal cells, including skin sensory neurons and epithelial cells of the intestine, lungs, urinary bladder, etc. TRPA1 is the major chemosensor that also responds to thermal and mechanical stimuli. Substances that

Alliaceous migraines.

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OBJECTIVE To report a migraineur with osmophobia and trigger to garlic and onion aroma. BACKGROUND While odors serve as a trigger in 70% of migraineurs, alliaceous aromas have been described only rarely. Furthermore, nor has more than one type of alliaceous odor acted as a trigger in the same

Proteinaceous cytotoxic component of Allium sativum induces apoptosis of INT-407 intestinal cells.

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Garlic has long been known for its wide array of therapeutic effects, including hypolipidemic, antihypertensive, antimicrobial, and possibly anticancer effects; conversely, some adverse effects of garlic, such as acute pain and neurogenic inflammation, have also been reported. However, information

TRPA1 receptors mediate environmental irritant-induced meningeal vasodilatation.

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The TRPA1 receptor is a member of the transient receptor potential (TRP) family of ion channels expressed in nociceptive neurons. TRPA1 receptors are targeted by pungent compounds from mustard and garlic and environmental irritants such as formaldehyde and acrolein. Ingestion or inhalation of these

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