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neurogenic inflammation/palavik
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8 tulemused
Clinical and experimental aspects of cutaneous neurogenic inflammation.
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Logi sisse
The aim of this paper is to present the state of knowledge on cutaneous neurogenic inflammation. Peripheral effector functions served by afferent sensory neurons underlie the so-called neurogenic inflammation. The mechanism of cutaneous neurogenic inflammation is connected with the release of
Warm SPA-induced hyperthermia confers protection to rats against airway inflammation evoked by capsaicin and substance P.
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Logi sisse
Solus par aqua (SPA) is a traditional health care therapy. Warm SPA may enhance immunity and cellular defense to protect body against diseases. The present study investigated whether the warm SPA could confer protection to neurogenic inflammation in rats. The rats were immersed in water where the
Nociception, neurogenic inflammation and thermoregulation in TRPV1 knockdown transgenic mice.
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Logi sisse
Transgenic mice with a small hairpin RNA construct interfering with the expression of transient receptor potential vanilloid 1 (TRPV1) were created by lentiviral transgenesis. TRPV1 expression level in transgenic mice was reduced to 8% while the expression of ankyrin repeat domain 1 (TRPA1) was
Warmth suppresses and desensitizes damage-sensing ion channel TRPA1.
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Logi sisse
BACKGROUND
Acute or chronic tissue damage induces an inflammatory response accompanied by pain and alterations in local tissue temperature. Recent studies revealed that the transient receptor potential A1 (TRPA1) channel is activated by a wide variety of substances that are released following tissue
Thermoregulation in brain injury.
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Logi sisse
Different mechanisms explain thermoregulatory dysfunction following ischemic stroke, hemorrhagic stroke, and traumatic brain injury. Temperature instability following brain injury likely involves hypothalamic injury, pathologic changes in cerebral blood flow, metabolic derangement, and a neurogenic
Neural pathways involved in infection-induced inflammation: recent insights and clinical implications.
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Logi sisse
Although the immune and nervous systems have long been considered independent biological systems, they turn out to mingle and interact extensively. The present review summarizes recent insights into the neural pathways activated by and involved in infection-induced inflammation and discusses
Capsaicin and sensory neurones: a historical perspective.
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Logi sisse
Capsaicin, the pungent ingredient of red pepper has become not only a "hot" topic in neuroscience but its new target-related unique actions have opened the door for the drug industry to introduce a new chapter of analgesics. After several lines of translational efforts with over 1,000 patents and
Temperature-dependent double spikes in C-nociceptors of neuropathic pain patients.
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Logi sisse
Five patients with small-fibre neuropathy characterized by temperature-dependent spontaneous pain, hyperalgesia/allodynia and signs of neurogenic inflammation were studied clinically and thermographically, and by microneurography. Thermography revealed hyperthermia confined to painful and
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