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phytohemagglutinin/rinnavähk

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ArtiklidKliinilistes uuringutesPatendid
Leht 1 alates 88 tulemused
Lymphocyte responsiveness in stimulation with phytohemagglutinin (PHA) and the inhibitory effect of autologous serum on lymphocyte responsiveness were investigated in 55 patients with breast cancer. Lymphocytes from patients, even in the late stage of the disease, as well as from normal healthy

Phytohemagglutinin-induced mitotic index in blood lymphocytes: a potential biomarker for breast cancer risk.

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
BACKGROUND Cell proliferation is associated with the pathogenesis of cancer because it provides opportunities for accumulating genetic mutations. However, biomarkers of cell proliferation in response to environmental stimuli have not been adequately explored for breast cancer risk. METHODS In a
Store-operated Ca(2+) entry (SOCE) is the main Ca(2+) entry pathway of non-excitable cells. In the past decade, the activation of this entry has been unveiled, with STIM1, a protein of the endoplasmic reticulum able to sense the intraluminal Ca(2+) content, and Orai1, the pore-forming unit of the

Effects of antiestrogen and progestin on immune functions in breast cancer patients.

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Logi sisse
Several immunologic variables were evaluated in 14 patients with untreated primary breast cancer and 20 postmastectomized patients undergoing tamoxifen (TAM) or high-dose medroxyprogesterone acetate (MPA) treatment. Immunologic evaluation in the peripheral blood included lymphocyte count, definition

[A case of limbic encephalitis associated with breast cancer developed in an HTLV-1 carrier].

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Logi sisse
We here present a case of 44-year-old woman, a carrier of human T-lymphotrophic virus type-1 (HTLV-1), who suffered from limbic encephalitis and breast cancer. In December 1997, the patient's behavior became abnormal. Three weeks later, she became markedly forgetful. At that time neurological

Deficient concanavalin-A-induced suppressor cell activity in women with untreated breast cancer.

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Logi sisse
Peripheral blood mononuclear cells from 14 women with untreated breast cancer and 5 patients with non-malignant breast disease were studied for concanavalin-A (Con A) inducible suppressor activity against proliferative response of lymphocytes to phytohemagglutinin (PHA). Six of 14 patients with

In vitro studies of axillary lymph node cells in patients with breast cancer.

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Logi sisse
A total of 170 axillary lymph nodes were obtained from fresh mastectomy specimens from 81 women with breast cancer. Lymph node cells were tested in vitro for T and B cells by the rosette technique and immunofluorescence microscopy and for functional capacity by response to the mitogens

Biological markers and breast cancer. A multiparametric study. II. Depressed immune competence.

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Logi sisse
Immune functions were evaluated in 207 carefully staged breast cancer patients, 54 patients with benign breast diseases and 152 normal controls. All patients were followed for at least five years and the prognostic significance of immune competence determined at diagnosis was established. The
In an attempt to identify lymphocyte subsets possibly involved in the response to malignant cells, we have studied the lymphocyte surface phenotype by using a panel of monoclonal antibodies on both peripheral blood lymphocytes (PBL) and histologically proven metastatic and nonmetastatic (i.e.,
Sera from cancer patients have been shown to suppress normal lymphoid cell responsiveness in vitro. In the present study, sera from breast cancer patients were demonstrated to be inhibitory to the concanavalin A (Con A)-, Proteus vulgaris-derived phytohemagglutinin-, and pokeweed mitogen-induced

[Cellular immunity in breast cancer patients].

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Logi sisse
84 breast cancer patients were examined prior to surgery regarding cellular immunity. 47 patients were free from secondary tumors, 37 already had axillary lymph node metastases, but no other secondary growth. 37 healthy women formed a control group. With reference to the total leukocyte count and to
The effects of radiation therapy and adjuvant chemoimmunotherapy on the immune competence of patients with breast cancer were investigated. The tests performed included intradermal tuberculin tests, T- and B-lymphocyte counts, and lymphocyte blast transformation tests; phytohemagglutinin (PHA),

The immunological status of breast cancer patients during treatment with a new antiestrogen, toremifene.

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
The immune status of breast cancer patients was followed during antiestrogen treatment for at least 1 year or until progression of the disease. Twelve post-menopausal women with advanced estrogen-receptor-positive breast cancer were treated with a novel antiestrogen, toremifene. Immune functions

Colonies formed in agar from human breast cancer and their identification as T-lymphocytes.

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Logi sisse
Single cell suspensions prepared from human breast cancer specimens by collagenase digestion were cultured in soft agar with phytohemagglutinin-stimulated human lymphocyte-conditioned medium (PHA-LCM). In 6 of 10 different tumors, PHA-LCM-dependent clonal growth was develop. After 12-14 days of

The information-theory analysis of Michaelis-Menten constants for detection of breast cancer.

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
BACKGROUND The Michaelis-Menten constants (K(m) and V(max)) operated by the Information Theory were employed for detection of breast cancer. METHODS The rate of enzymatic hydrolysis of fluorescein diacetate (FDA) in live peripheral blood mononuclear cells (PBMC), derived from healthy subjects and
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