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piperidine/hypoxia
Link salvestatakse lõikelauale
12 tulemused
Piperidine compounds for treating anoxia, cerebral ischemia migraine or epilepsy
Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
The present invention relates to therapeutically active piperidine compounds, a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in the treatment of anoxia, traumatic injury, ischemia, migraine and epilepsy.
It is well known
Piperidine compounds and their preparation and use
Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
The present invention relates to therapeutically active piperidine compounds, a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in the treatment of anoxia, ischemia, migraine and epilepsy.
It is well known that accumulation of
Piperidine compounds and their preparation and use
Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
The present invention relates to therapeutically active piperidine compounds, a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in the treatment of anoxia, ischemia, migraine and epilepsy.
It is well known that accumulation of
Piperidine compounds and their preparation and use
Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
The present invention relate s to therapeutically active piperidine compounds, a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in the treatment of anoxia, ischemia, migraine and epilepsy.
It is well known that accumulation of
Substituted piperidine compounds and their use
Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
The present invention relates to therapeutically active piperidine compounds, a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in the treatment of anoxia, traumatic injury, ischemia, migraine and epilepsy.
It is well known
Piperidine compounds and pharmaceutical compositions thereof
Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
The present invention relates to therapeutically active piperidine compounds, a method of preparing the same, pharmaceutical compositions comprising the compounds and to a method of treating therewith. The novel compounds are useful in the treatment of anoxia, ischemia, migraine and epilepsy.
It is
Piperidine compounds and their preparation and use
Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
The invention will now be described in further detail with reference to the following examples:
Example 1
(-)-trans-4-(-4-fluorophenyl)-3-(3,4-methylenedioxyphenoxymethyl)-1-pentylp iperidine hydrochloride
10g of (-)-trans-4-(-4-fluorophenyl)-3,4-methylenedioxyphenoxymethyl)-piperidine hydrochloride
Weakly basic 2-nitroimidazoles for the non-invasive detection of tissue hypoxia
Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
FIELD OF THE INVENTION
This invention relates to weakly basic derivatives of 2-nitroimidazoles (pKa about 8 or greater) and their penultimate chemical precursors that are useful for the non-invasive measurement of cellular hypoxia in normal and cancer tissue by means of positron emission tomography
4-hydroxy-4-methyl-piperidine-1-carboxylic acid (4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-amide
Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
FIELD OF THE INVENTION
The present invention relates to 4-hydroxy-4-methyl-piperidine-1-carboxylic acid(4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-amide, which is a compound of formula
##STR00002## and to pharmaceutically acceptable acid addition salts thereof. This compound is generically
Method of treating calcium overload in brain cells of mammals
Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
The present invention relates to therapeutically active piperidine compounds, a method of preparing the same, pharmaceutical compositions comprising the compounds and to a method of treating therewith. The novel compounds are useful in the treatment of anoxia, ischemia, migraine and epilepsy.
It is
Method of treating calcium overload
Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
The present invention relates to therapeutically active piperidine compounds, a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in the treatment of anoxia, ischemia, migraine and epilepsy.
It is well known that accumulation of
Alkyl and cycloalkylthiophenylalkylaminoalkanols, their salts and the preparation thereof
Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
This invention relates to alkyl and cycloalkylthiophenylalkylaminoalkanols, to the salts of these latter by addition of organic or inorganic acids, and also to the preparation of these compounds.
The present invention provides an amino-alcohol having the formula: ##STR2## wherein R.sub.1 represents
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