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polycythemia/tyrosine

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10 tulemused

Thrombopoietin signaling defect in polycythemia vera platelets

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Logi sisse
BACKGROUND OF THE INVENTION Polycythemia vera (PV), idiopathic myelofibrosis (IMF), chronic myelogenous leukemia (CML) and essential thrombocythemia (ET) are classified as the chronic myeloproliferative disorders because their pathophysiology involves the clonal expansion of a multipotent

Methods to assay a thrombopoietin signaling defect in polycythemia vera platelets

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
BACKGROUND OF THE INVENTION Polycythemia vera (PV), idiopathic myelofibrosis (IMF), chronic myelogenous leukemia (CML) and essential thrombocythemia (ET) are classified as the chronic myeloproliferative disorders because their pathophysiology involves the clonal expansion of a multipotent

Identification of a JAK2 mutation in polycythemia vera

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
The present invention concerns the V617F variant of the protein-tyrosine kinase JAK2, said variant being responsible for Vaquez Polyglobulia. The invention also relates to a first intention diagnostic method for erythrocytosis and thrombocytosis allowing their association with myeloproliferative

Identification of a JAK2 mutation in polycythemia vera

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
The present invention concerns the V617F variant of the protein-tyrosine kinase JAK2, said variant being responsible for Vaquez Polyglobulia. The invention also relates to a first intention diagnostic method for erythrocytosis and thrombocytosis allowing their association with myeloproliferative

Identification of a JAK2 mutation in Polycythemia Vera

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
The present invention concerns the V617F variant of the protein-tyrosine kinase JAK2, said variant being responsible for Vaquez Polyglobulia. The invention also relates to a first intention diagnostic method for erythrocytosis and thrombocytosis allowing their association with myeloproliferative

Identification of a JAK2 mutation in Polycythemia Vera

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
The present invention concerns the V617F variant of the protein-tyrosine kinase JAK2, said variant being responsible for Vaquez Polyglobulia. The invention also relates to a first intention diagnostic method for erythrocytosis and thrombocytosis allowing their association with myeloproliferative

Antibodies to the cytoplasmic domain of the thrombopoietin receptor

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
BACKGROUND OF THE INVENTION Polycythemia vera (PV), idiopathic myelofibrosis (IMF), chronic myelogenous leukemia (CML) and essential thrombocythemia (ET) are classified as the chronic myeloproliferative disorders because their pathophysiology involves the clonal expansion of a multipotent

Identification of a JAK2 mutation involved in vaquez polyglobulia

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
The present invention concerns the V617F variant of the protein-tyrosine kinase JAK2, said variant being responsible for Vaquez Polyglobulia. The invention also relates to a first intention diagnostic method for erythrocytosis and thrombocytosis allowing their association with myeloproliferative

Identification of a JAK2 mutation involved in vaquez polyglobulia

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
The present invention concerns the V617F variant of the protein-tyrosine kinase JAK2, said variant being responsible for Vaquez Polyglobulia. The invention also relates to a first intention diagnostic method for erythrocytosis and thrombocytosis allowing their association with myeloproliferative

Identification of a JAK2 mutation involved in Vaquez Polyglobulia

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
This application is a National Stage application of PCT/EP2005/055586, filed Oct. 26, 2005, which claims priority from French patent application FR 0411480, filed Oct. 27, 2004. The entire contents of each of the aforementioned applications are incorporated herein by reference. The present invention
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