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prostaglandin/diarrhea
Link salvestatakse lõikelauale
10 tulemused
Preventing enteropooling induced diarrhea by prostacyclin or 11-oxo-prostaglandin administration
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BACKGROUND OF THE INVENTION
Numerous agents, such as diarrheogenic prostaglandins, various parasitic oranisms, and toxins produced by microbial agents, are known in the art to have a recognized diarrheogenic potential in mammals. One measure of the potential for the induction of diarrhea for a given
2-Substituted prostaglandins
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BACKGROUND OF THE INVENTION
U.S. Pat. Nos. 3,965,143; 4,087,621; 4,060,691 and 4,322,543 extensively disclose 16 alkyl, 16 hydroxy prostaglandins. Compounds of the present invention structurally differ from the prior art compounds by substitution at the 2 position. For example, the prior art
Tetrahydrocarbazole 1-alkanoic acids, pharmaceutical compositions and use
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BACKGROUND OF THE INVENTION
This invention relates to prostaglandin antagonists useful in treating a variety of conditions, such as allergic asthma where excessive contractile activity of prostaglandins and prostaglandin biosynthetic intermediates occur.
These compounds antagonize the actions of
Tetrahydrocarbazole 1-alkanoic acids and pharmaecutical compositions
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BACKGROUND OF THE INVENTION
This invention relates to prostaglandin antagonists useful in treating a variety of conditions, such as allergic asthma where excessive contractile activity of prostaglandins and prostaglandin biosynthetic intermediates occur.
These compounds antagonize the actions of
Indole-2-alkanoic acids compositions of and anti allergic use thereof
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SUMMARY OF THE INVENTION
This invention relates to prostaglandin antagonists useful in treating a variety of conditions, such as allergic asthma where excessive contractile activity of prostaglandins and prostaglandin biosynthetic intermediates occur.
These compounds antagonize the actions of
Tetrahydrocarbazole esters, pharmaceutical compositions and use
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BACKGROUND OF THE INVENTION
This invention relates to prostaglandin antagonists useful in treating a variety of conditions, such as allergic asthma where excessive contractile activity of prostaglandins and prostaglandin biosynthetic intermediates occur.
These compounds antagonize the actions of
Cyclohept(B)indolealkanoic acids, pharmaceutical compositions and use
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DESCRIPTION OF THE INVENTION
The present invention relates to novel compounds of Formula I: ##STR1## wherein: A is --(CR.sup.9 R.sup.10).sub.r R.sup.11 ;
R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and R.sup.6 are each independently selected from:
(1) hydrogen;
(2) alkyl having 1 to 6 carbon
Cyclohept[b]indoleakanoic acids, pharmaceutical compositions and use
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BACKGROUND OF THE INVENTION
This invention relates to prostaglandin antagonists useful in treating a variety of conditions, such as allergic asthma where excessive contractile activity of prostaglandins and prostaglandin biosynthetic intermediates occur.
These compounds antagonize the actions of
Cyclohept[b]indolealkanoic acids, pharmaceutical compositions and use
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Logi sisse
BACKGROUND OF THE INVENTION
This invention relates to prostaglandin antagonists useful in treating a variety of conditions, such as allergic asthma where excessive contractile activity of prostaglandins and prostaglandin biosynthetic intermediates occur.
These compounds antagonize the actions of
Cyclohept[b]indolealkanoic acids, pharmaceutical compositions and use
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DESCRIPTION OF THE INVENTION
The present invention relates to novel compounds of Formula I: ##STR1## wherein:
A is --(CR.sup.9 R.sup.10).sub.r R.sup.11 ; R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and R.sup.6 are each independently selected from:
(1) hydrogen;
(2) alkyl having 1 to 6 carbon
Kõige täiuslikum ravimtaimede andmebaas, mida toetab teadus
- Töötab 55 keeles
- Taimsed ravimid, mida toetab teadus
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- Korraldage oma huvisid ja hoidke end kursis uudisteuuringute, kliiniliste uuringute ja patentidega
Sisestage sümptom või haigus ja lugege ravimtaimede kohta, mis võivad aidata, tippige ürdi ja vaadake haigusi ja sümptomeid, mille vastu seda kasutatakse.
* Kogu teave põhineb avaldatud teaduslikel uuringutel
