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rhinitis/protease

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6 tulemused

Secretory leukocyte protease inhibitor as an inhibitor of tryptase

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Logi sisse
FIELD This invention relates to inhibition of proteases, and more particularly, to inhibition of tryptase by secretory leukocyte protease inhibitor (SLPI). BACKGROUND Vasoactive intestinal peptide (VIP) is a bronchorelaxant which is absent from or present only at relatively low levels in the lungs

Peptidyl heterocyclic ketones useful as tryptase inhibitors

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Logi sisse
FIELD OF THE INVENTION This invention relates to a series of compounds which are peptidyl heterocyclic ketone inflammatory cell serine protease inhibitors and their compositions and methods for the prevention and treatment of a variety of immunomediated inflammatory disorders, skin

Peptidyl heterocyclic ketones useful as tryptase inhibitors

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
FIELD OF THE INVENTION This invention relates to a series of compounds which are peptidyl heterocyclic ketone inflammatory cell serine protease inhibitors and their compositions and methods for the prevention and treatment of a variety of immunomediated inflammatory disorders, skin

Compositions and methods for treating mast-cell mediated conditions

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Logi sisse
BACKGROUND OF THE INVENTION 1. Field of the Invention This invention relates to compositions and methods effective for the prevention and treatment of mast-cell mediated inflammatory disorders. The invention includes compositions and methods effective for the prevention and treatment of inflammatory

Compositions comprising a substituted benzimidazole useful for treating immunomediated inflammatory disorders

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Logi sisse
DESCRIPTION OF THE FIELD Tryptase, the predominant protease secreted from human mast cells, is thought to be involved in neuropeptide processing and tissue inflammation. Tryptase concentrations are elevated in the bloodstream for several hours following anaphylaxis (Schwartz et al. (1987) N. Eng. J.

Compositions and methods for treating mast-cell mediated conditions

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
BACKGROUND OF THE INVENTION 1. Field of the Invention This invention relates to compositions and methods effective for the prevention and treatment of mast-cell mediated inflammatory disorders. The invention includes compositions and methods effective for the prevention and treatment of inflammatory
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