rhodiola/vähivastane

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[Ethanol extract of Rhodiola rosea L. regulates the number of tumor infiltrating T cells to enhance antitumor effect in Lewis lung cancer-bearing mice].

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Objective To explore the anti-tumor immune function of the Tibetan medicine Rhodiola rosea L. (RRL). Methods Lewis lung cancer-bearing mice were randomly divided into normal saline group, 500 mg/kg RRL ethanol extract treatment group, and 10 mg/kg cyclophosphamide (CTX) treatment group. All the

Antitumor effects of a purified polysaccharide from Rhodiola rosea and its action mechanism.

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In the last three decades, numerous polysaccharides and polysaccharide-protein complexes have been isolated from plant or animal and used as a promising source of therapeutic agents for cancer. In this study, we prepared a homogeneous polysaccharide (RRP-ws) from Rhodiola rosea and tested its

Antineoplastic effects of Rhodiola crenulata treatment on B16-F10 melanoma.

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Melanoma is an aggressive form of skin cancer with limited treatment options for advanced stage disease. Early detection and wide surgical excision remain the initial mode of treatment for primary tumors thus preventing metastases and leading to improved prognosis. Through this work, we have

[Anti-tumor metastatic constituents from Rhodiola wallichiana].

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To study the anti-tumor metastatic constituents in Rhodiola wallichiana (HK) S H Fu var Cholaensis (Praeg) S H Fu, chemical constituents were isolated and purified by repeated column chromatography (silica gel, Toyopearl HW-40C and preparative HPLC). Their structures were elucidated on the basis of

Inhibition of autophagy enhances synergistic effects of Salidroside and anti-tumor agents against colorectal cancer.

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BACKGROUND Various plant extracts have been suggested to be used as auxiliary agents in chemotherapy considering their anti-proliferative effect on cancer cells. However, recent reports reveal that plant extracts may function as inducers of autophagy of cancer cells. In general, autophagy confers

Anticancer effect of salidroside on A549 lung cancer cells through inhibition of oxidative stress and phospho-p38 expression.

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Oxidative stress is important in carcinogenesis and metastasis. Salidroside, a phenylpropanoid glycoside isolated from Rhodiola rosea L., shows potent antioxidant properties. The aim of the present study was to investigate the roles of salidroside in cell proliferation, the cell cycle, apoptosis,

Salidroside alleviates cachexia symptoms in mouse models of cancer cachexia via activating mTOR signalling.

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BACKGROUND Cachexia has a devastating impact on survival and quality of life for many cancer patients and contributes to nearly one-third of all cancer deaths; also, it is associated with poor responses to chemotherapy and survival. A better understanding of the underlying mechanisms of

[Effect of a Rhodiola extract on the tumor process in an experiment].

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Antitumor and antimetastatic effects of an official extract of Rhodiola rosea were established in experiments on inbred and noninbred mice and rats with transplantable NK/Ly tumor, Ehrlich's adenocarcinoma, melanoma B16 and Lewis lung carcinoma. Application of the said preparation to

Systems pharmacology unravels the synergic target space and therapeutic potential of Rhodiola rosea L. for non-small cell lung cancer

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Background: Lung cancer is the most common and mortal cancer worldwide. Rhodiola rosea L. (RR), a well-known traditional Chinese medicine (TCM), has been turned out to be effective in anti-lung cancer therapy, but its molecular mechanism

[Rhodiola sachalinensis suppresses T241 fibrosarcoma tumor cells proliferation in vitro and growth in vivo].

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OBJECTIVE To study the anticancer activity of Rhodiola sachalinensis in vitro and in vivo experiments. METHODS The effect of Rhodiola sachalinensis extracts at various concentrations on T241 fibrosarcoma cells proliferation and cytotoxic potential were measured. We divided T241 fibrosarcoma-bearing

Antiproliferative and antimitotic effect, S phase accumulation and induction of apoptosis and necrosis after treatment of extract from Rhodiola rosea rhizomes on HL-60 cells.

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Rhodiola rosea is a medicinal plant having stimulating and adaptogenic properties, and some reports also indicate its anticancer and antimutagenic effect. However, the mechanism of its anticancer effect is unknown as there have been no cytological studies regarding cytostatics, cell cycle, induction

Pause menopause with Rhodiola rosea, a natural selective estrogen receptor modulator.

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BACKGROUND Menopausal women are challenged by the adverse effects of estrogen loss on energy, mood, cognitive function, and memory. These stresses are compounded by increased risks for cardiovascular disease, osteoporosis, and cancer. Known to have neuroprotective, cardio-protective, anti-oxidative

Aqueous extract of Rhodiola imbricata rhizome stimulates Toll-like receptor 4, granzyme-B and Th1 cytokines in vitro.

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Rhodiola imbricata is a medicinal plant, native to mountainous regions of Asia, parts of Europe, and the Arctic. Traditionally it is recommended to help combat fatigue and restore energy. It exhibits anti-stress, anti-cancer, and immunostimulatory activities. However, the effect of Rhodiola on

Approaches of Rhodiola kirilowii and Rhodiola rosea field cultivation in Poland and their potential health benefits.

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Numerous researches have been carried out on plants of the Rhodiola species, especially Rhodiola kirilowii (Regel) Maxim. and Rhodiola rosea. Various compounds have been reported to be isolated from R. kirilowii and R. rosea, including cyanogenic glycosides, monoterpene alcohols and their

Aqueous extract of Rhodiola imbricata rhizome inhibits proliferation of an erythroleukemic cell line K-562 by inducing apoptosis and cell cycle arrest at G2/M phase.

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Rhodiola imbricata is a medicinal plant having immunostimulating properties. The anti-proliferative effects of Rhodiola aqueous extract (RAE), were studied in human erythroleukemic cell line K-562 using MTT cell proliferation assay. The proliferation of K-562 was significantly decreased after 72h

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