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serotonin/insult

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Leht 1 alates 45 tulemused

Psychophysiological Study of Pain Perception in Depressed Patients With Suicidal Risk

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
Aim: The first objective of this project is to test different pain mechanisms that could be involved in the increase of pain thresholds and tolerance in suicidal patients. The second objective is to test whether there's a loss of pleasantness during social touch in suicidal patients. The main aim is

Neuroinflammation and Modulating Factors in Depression and HIV

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
Depression in HIV is a complex co-morbidity with both social factors such as stigma as well as biologic components. Disruptions in neurotransmitters such as serotonin and catecholamines are known to cause depression. Inflammation caused by diseases such as stroke, diabetes, and HIV is associated

Dose-finding Study of Selective Serotonin Reuptake Inhibitors to Enhance Neuroplasticity

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
The brain is able to change throughout life in response to learning, or injury, or to adapt to changes in the environment, which is known as neuroplasticity. Stroke survivors suffer disabling chronic motor impairments that have proven challenging to improve. Increasing neuroplasticity using

Rehabilomics Study in Stroke Patients After Robotic Rehabilitation

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
Epigenetic and single-nucleotide polymorphisms (SNPs) in genes may influence an individual's capacity for use-dependent plasticity, and hence their responsiveness to post-stroke rehabilitation. Understanding genetic variation gives clinicians a biological signal that could be used to predict who is

7-day Atorvastatin and Emotional Processing

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
Depression is common and associated with considerable health disability. Traditional antidepressants mainly work by modulating monoamine levels in the synaptic cleft; however, the evidence that depression is caused by impaired serotonin or noradrenaline activity is weak and inconsistent, and indeed

Transcranial Alternating Current Stimulation Treating Post-stroke Depression

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
Patients with post-stroke depression (PSD) have more dysfunction, poorer recovery outcomes, and higher morbidity and mortality in the first year after stroke onset than those patients without stroke. Some therapeutic methods have shown to be effective for PSD, including antidepressants, non-drug

Post Stroke Intensive Rehabilitation

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
Despite progress in the treatment of cerebrovascular diseases in the acute phase, stroke remains a catastrophic event with important public health implications. Post-acute intensive rehabilitation is recommended in patients with neurological deficits, but standardized evaluation protocols are

Escitalopram and Language Intervention for Subacute Aphasia

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
In this project, the investigators will investigate the effects of a selective serotonin reuptake inhibitor (SSRI), escitalopram, on augmenting language therapy effectiveness, as measured by naming untrained pictures and describing pictures, in individuals with aphasia in the acute and subacute post

Effects of Music Therapy on Mood, Pain, Patient and Staff Satisfaction on Adult Inpatient Neurological Units?

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
Objective: Does music therapy improve mood, pain and patient satisfaction on adult inpatient neurological units? Is music therapy an acceptable and feasible intervention in an adult inpatient neurological unit based on patient, family, and care provider satisfaction measures? Population: Foothills

Microvascular Dysfunction in Obesity

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
Twenty-five sedentary class 2 and above obese [body mass index (BMI) >35 kg/m2, waist circumference >40 inches (men) or >35 inches (women)] men and women (18-45 yrs) will participate in these experiments. Individuals under 18 years of age will not be investigated due to the invasive nature of the

Migraine Relief After Patent Foramen Ovale Closure: a Single Center Analysis

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
The Study will evaluate the results of approximately 100 subjects from a single center study registered in this trial. Subjects who experienced transient ischemic attack (TIA) or stroke with a clinical indication to PFO closure and symptomatic for migraine with/o aura are considered for a migraine
Stroke or unsufficient cerebral circulation is a non-traumatic disease due to occlusion or rupture of brain blood circulation characterized by neurological deficits such as loss of motor control, cognitive impairment, oral disorder or sensory changes in one half of the body resulting from changes.

Fluoxetine Opens Window to Improve Motor Recovery After Stroke

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
FLOW Trial is a randomized, placebo-controlled, blinded phase II trial evaluating the efficacy of coupling antidepressant therapy (e.g., selective serotonin reuptake inhibitor - fluoxetine) with exercise rehabilitation across multiple Canadian sites in 176 stroke patients. 88 patients will be

Topical 10 % Nifedipine Versus 5% Sildenafil in Secondary Raynaud

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
Raynaud's phenomenon (RP) is an exaggerated vascular response characterized by at least biphasic change (pallor and cyanosis) in the skin color of the digits, induced by cold temperature or emotional stress, The prevalence varies from 3 to 5%. In primary RP, there is no evidence of a secondary cause

TSK (Tryptophan - Serotonin - Kynurenine) Biomarkers Assessment in Stroke

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
Tryptophan (TRP), an essential aminoacid, is metabolized in the serotonin (5-HT) or in the kynurenine (KYN) pathway. Serotonin is catabolized to 5-HIAA (5-hydroxyindole amino acid) by monoamine oxidase A (MAOA). The TRP to KYN transformation is regulated by indoleamine 2,3-dioxygenase (IDO). The
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