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serotonin/vähk

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Leht 1 alates 20 tulemused

Use of serotonin agents for adjunct therapy in the treatment of cancer

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FIELD OF THE INVENTION This invention relates to the use of serotonin agents in the treatment of malignancies. More specifically, this invention relates to the use of agents that affect serotonin neurotransmission, e.g., serotonergic agents, serotonin reuptake inhibitors and selective serotonin

Methods of treating and preventing leukemia and other cancers of the blood and bone

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FIELD OF THE INVENTION This invention is in the field of preventing and treating leukemia and other cancers, especially those of the blood and bone, as well as other disorders of the blood, by increasing osteoblast proliferation, preferably by inhibiting serotonin. BACKGROUND OF THE

Method for treatment of cancer and infectious disease

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Logi sisse
FIELD OF THE INVENTION The present invention concerns a pharmaceutical preparation or system for activation of natural killer cells (NK-cells), in order, for example, to treat tumors or virus infections. SUMMARY OF THE INVENTION Natural killer cells (NK-cells) are a group of spontaneously cytotoxic

Method for treatment of cancer and infectious disease

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
FIELD OF THE INVENTION The present invention concerns a pharmaceutical preparation or system for activation of natural killer cells (NK-cells), in order, for example, to treat tumors or virus infections. SUMMARY OF THE INVENTION Natural killer cells (NK-cells) are a group of spontaneously cytotoxic

Method of medical treatment with serotonin antagonists

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Logi sisse
BACKGROUND OF INVENTION (a) Field of the Invention This invention relates to a method of treatment of conditions such as bladder carcinoma, lung carcinoma, breast carcinoma, carcinoma of adrenal cortex, or pancreatic carcinoma by serotonin antagonists and primarily cyproheptadine. (b) Description of
FIELD OF THE INVENTION The present invention concerns a pharmaceutical preparation or system for activation of natural killer cells (NK-cells), in order for example, to treat tumors or virus infections. BACKGROUND OF THE INVENTION Natural killer cells (NK-cells) are a group of spontaneously

N-cyano-N'-pyridylguanidines as serotonin antagonists

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Logi sisse
The present invention relates to a series of compounds, their pharmaceutically acceptable salts, and their N-oxides, to methods for preparing the said compounds, salts or N-oxides, to pharmaceutical compositions containing said compounds, to dosage units of the compositions, and to methods of

Spirocyclic compounds as tryptophan hydroxylase inhibitors

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Logi sisse
FIELD OF THE INVENTION The present invention is directed to spirocyclic compounds which are inhibitors of tryptophan hydroxylase (TPH), particularly isoform 1 (TPH1), that are useful in the treatment of diseases or disorders associated with peripheral serotonin including, for example,

Spirocyclic compounds as tryptophan hydroxylase inhibitors

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
FIELD OF THE INVENTION The present invention is directed to spirocyclic compounds which are inhibitors of tryptophan hydroxylase (TPH), particularly isoform 1 (TPH1), that are useful in the treatment of diseases or disorders associated with peripheral serotonin including, for example,

Spirocyclic compounds as tryptophan hydroxylase inhibitors

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
FIELD OF THE INVENTION The present invention is directed to spirocyclic compounds which are inhibitors of tryptophan hydroxylase (TPH), particularly isoform 1 (TPH1), that are useful in the treatment of diseases or disorders associated with peripheral serotonin including, for example,

Spirocyclic compounds as tryptophan hydroxylase inhibitors

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
FIELD OF THE INVENTION The present invention is directed to spirocyclic compounds which are inhibitors of tryptophan hydroxylase (TPH), particularly isoform 1 (TPH1), that are useful in the treatment of diseases or disorders associated with peripheral serotonin including, for example,

Spirocyclic compounds as tryptophan hydroxylase inhibitors

Ainult registreeritud kasutajad saavad artikleid tõlkida
Logi sisse
FIELD OF THE INVENTION The present invention is directed to spirocyclic compounds which are inhibitors of tryptophan hydroxylase (TPH), particularly isoform 1 (TPH1), that are useful in the treatment of diseases or disorders associated with peripheral serotonin including, for example,

Pyrazinooxazepine derivatives

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Logi sisse
This application is a U.S. national stage of International Application No. PCT/JP2010/060408 filed Jun. 14, 2010. TECHNICAL FIELD OF THE INVENTION The present invention relates to a pyrazinooxazepine derivative having a superior serotonin 5-HT.sub.2C receptor activating action and useful as an agent
FIELD OF THE INVENTION The present invention relates to processes for the preparation of (R)-1-(5-chloro-[1,1'-biphenyl]-2-yl)-2,2,2-trifluoroethanol, 1-(5-chloro-[1,1'-biphenyl]-2-yl)-2,2,2-trifluoroethanone, and intermediates thereof, which are useful in the synthesis of inhibitors of TPH1 for the
FIELD OF THE INVENTION The present invention relates to processes for the preparation of (R)-1-(5-chloro-[1,1'-biphenyl]-2-yl)-2,2,2-trifluoroethanol, 1-(5-chloro-[1,1'-biphenyl]-2-yl)-2,2,2-trifluoroethanone, and intermediates thereof, which are useful in the synthesis of inhibitors of TPH1 for the
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