3 tulemused
Experimental protocol
- Double-blind, randomized, placebo-controlled cross-over trial
- 6-week intervention trial
- Experimental intervention (PhytoDyNAmic) = 6 capsules per day
- Placebo (inulin) = 1 g per day b.i.d.
- Administration = 3 capsules with breakfast and 3 capsules with dinner
- Wash-out
The optimal daily dose of metformin is thought to be 2000 mg, however patients with metformin intolerance cannot reach this target dose. Participate in this study are metformin intolerant. Metformin intolerant patients have been defined as those not able to be treated with the metformin daily dose
The process of the study, the choice of the patients, the collection and the processing of data A. Potential participants of study will be familiarized with the course of research in every detail before entering the study and after signing of an informed consent they will be examined by