Participants receive intravenous bolus of 1ml (20 mg) Hyoscine

Participants receive intravenous bolus of 1ml normal saline

Labor Long

Intervention is given once a participant is in established labor

Hyoscine Butylbromide

Placebo

National University Malaysia Medical Centre

The Effect of Hyoscine-N-butylbromide (HBB, Buscopan) in Augmented Labour Among Primigravidae

A Randomised Control Study: The Effect of Hyoscine-N-butylbromide (HBB, Buscopan) in Augmented Labour Among Primigravidae

Mean duration of first stage of labor in hours

Mean duration of second stage of labour in hours

Mean duration of third stage of labour in hours

Percentage of participants who delivered vaginally or via caesarean section

Percentage of neonates require admission to neonatal intensive care unit admission

Percentage of participants who develop side effects to treatment

Rahana Abd Rahman

Co-primary investigator

National University of Malaysia

Comparison between participants who receive hyoscine and those who do not.

Participants and care provider are blinded from the treatment

Anti-spasmodics

Gastric Peristalsis

Non-sedative Endoscopy

The experimental group was taken with Phloroglucin(Flospan®) before endoscopy.

Phloroglucin(Flospan®)

The control group was treated with normal saline before endoscopy

Normal saline

KeimyungUniversity

Effect of Oral Phloroglucin (Flospan®) as Premedication of Non-sedative Diagnostic Esophagogastroduodenoscopy

Effect of Oral Phloroglucin (Flospan®) as Premedication of Non-sedative Diagnostic Esophagogastroduodenoscopy: Single Center, Prospective, Double Blinded, Randomized Controlled Trial

Modified peristalsis grade (No, weak, moderate, severe, very severe)

Simplified discomfort grade questionnaire (Very easy, easy, so so, difficult)

Taste grade (Poor, bad, so so, good, very good)

YooJin Lee

Professor

Keimyung University Dongsan Medical Center

Hyoscine butylbromide 10mg oral single dose

Acetaminophen 15mg/kg oral single dose (maximum 1000mg)

Abdomen, Acute

Children

Acetaminophen, Analgesics, Non-Narcotic

Hyoscine butylbromide, Analgesics, Non-Narcotic

London Health Sciences Centre

Buscopan Versus Acetaminophen for Acute Abdominal Pain in Children

Hyoscine Hydrobromide (Buscopan) Versus Acetaminophen for Acute Abdominal Pain in Children: A Randomized Controlled Trial

Pain severity on a 100 mm Visual Analog Scale (VAS)

Pain severity on Faces Pain Scale - Revised and VAS

Time to Achieve 20% Reduction in Faces Pain Score - Revised from time 0

Proportion of participants that achieve a pain score < 30 mm on the VAS

Satisfaction scores on 5-Item Likert Scale

Proportion of participants with return visits for surgical pathology

Lawson Health Research Institute

Colonic Adenomas

Hyoscine Butyl Bromide 20mg/2 ml i.v.is administered at time of caecal intubation

Hyoscine Butyl Bromide 20mg/2 ml i.v.

Administration of Saline 2 ml at time of caecal intubation

Saline 2 ml i.v.

Ospedale Valduce

Does the Hyoscine N-Butylbromide Administered During Colonoscopy Increase the Adenoma Detection Rate?

Does Hyoscine N-butylbromide Administered During Colonoscopy Increase the Polyp Detection Rate? a Randomized, Single Center, Double Blind, Placebo-controlled Study

As indirect estimation of the amount of air retained in the abdomen at the end of the procedure, the DAC (difference in the abdominal circumference measured before and after colonoscopy) was also calculated. At discharge (at least 1 hour after colonoscopy) the bloating perceived by the patient was measured by means of a VA scale (range 0-100).

tachycardia/hyoscine

The Effect of Hyoscine-N-butylbromide (HBB, Buscopan) in Augmented Labour Among Primigravidae

Effect of Oral Phloroglucin (Flospan®) as Premedication of Non-sedative Diagnostic Esophagogastroduodenoscopy

Buscopan Versus Acetaminophen for Acute Abdominal Pain in Children

Does the Hyoscine N-Butylbromide Administered During Colonoscopy Increase the Adenoma Detection Rate?

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