Group I patients received 25 gram of sugar (pudding) and 50 cc of coconut milk as late night snack for a month

Group II patients received 50 gram of sugar (25 gram pudding and 25 gram syrup) as late night snack for a month

Malnutrition

Cirrhosis, Liver

50 cc of coconut milk supplementation plus 25 gram sugar (pudding) was given to cirrhosis patients as late night snack

coconut milk

Hepatobiliary Division

Effect of Coconut Milk Supplementation to Improve Nutritional Status in Cirrhosis Patient

Beneficial Effects of Coconut Milk Supplementation to Improve Nutritional Status in Patients With Liver Cirrhosis

Body mass index is calculated by divided weight (in kg) with square of height (in meter). Unit of measure: kg/m2

Triceps skinfold thickness is calculated by skinfold calliper. Unit of measure: millimeter (mm)

Mid arm muscle circumference is calculate by formula as follow:
MAMC = MUAC - (TSF x 3.14). MUAC (mid upper arm circumference). Unit of measure: milimeter (mm)

Body fat mass is calculated by calliper by pulling the fat away from the muscles, pinch them with the caliper, take the measurements, and look at a chart to figure out. Unit of measure : kg

Prealbumin serum is checked by nephelometry technique with nephelometer laser, albumin serum is checked by bromcresol green method, using ABX cobas. Both of that in milligram per deciliter (mg/dL)

Rino Alvani Gani

Head of Hepatobiliary

Dr Cipto Mangunkusumo General Hospital

The patients were divided into 2 groups, groups I received 25 g of sugar plus 50 cc of coconut milk (200 kkal) as late night snacks (LNS); and group II received 50 g of sugar alone (200 kkal) as LNS

The diet/supplement group will be asked to follow a low-fat, vegan diet for 20 weeks, and take a vitamin B12 supplement daily.

The supplement group will be asked to take a daily vitamin B12 supplement, and to make no changes to their current diet.

Diabetic Neuropathy

A low-fat, vegan diet (no meat, fish, eggs or dairy products) and a vitamin B12 supplement in the form of 2000mcg of methylcobalamin

Vegan diet and vitamin B12 supplement

A daily vitamin B12 supplement in the form of 2000mcg of methylcobalamin

Vitamin B12 supplement

Physicians Committee for Responsible Medicine

A Nutritional Intervention for Diabetic Neuropathy (WCCR-DN2)

Pain will be measured follow the baseline and 20 week score using the following assessment tools:
Michigan Neuropathy Screening Instrument Norfolk Quality of Life Questionnaire Neuropathy Impairment Score - Lower Limbs Neuropathy Total Symptom Score 6 Neuropathy Pain Scale McGill Pain Questionnaire Global Impression Scale

Sensation will be measured follow the baseline and 20 week score using the following assessment tools:
Michigan Neuropathy Screening Instrument Norfolk Quality of Life Questionnaire Neuropathy Impairment Score - Lower Limbs Neuropathy Total Symptom Score 6

Disease activity will be measured by change in galvanic skin response, as measured by Sudoscan technology. Galvanic skin response detects sweat gland function, which is an indicator of small nerve fiber function..

Glycemic control will be measured by change in hemoglobin A1c percentage points at baseline and 20 weeks.

Mood will be measured by change in score using the following assessment tools at baseline and 20 weeks:
Beck Depression Inventory Center for Epidemiologic Studies Depression Scale Revised

Quality of Life will be measured by change in score using the following assessment tools at baseline and 20 weeks:
Norfolk Quality of Life Questionnaire MOS SF-36 Questionnaire

Acceptability of vegan diet will be measured by change in score at baseline and 20 weeks using the Eating Inventory questionnaire.

A Nutritional Intervention for Diabetic Neuropathy

Pain will be measured follow the baseline and 20 week score using n the following assessment tools:
Michigan Neuropathy Screening Instrument
Norfolk Quality of Life Questionnaire
Neuropathy Impairment Score - Lower Limbs
Neuropathy Total Symptom Score 6
Neuropathy Pain Scale
McGill Pain Questionnaire
Global Impression Scale

Sensation will be measured follow the baseline and 20 week score using the following assessment tools:
Michigan Neuropathy Screening Instrument
Norfolk Quality of Life Questionnaire
Neuropathy Impairment Score - Lower Limbs
Neuropathy Total Symptom Score 6

Disease activity will be measured by change in small fiber density of lower limbs as measured by skin biospy done at baseline and 20 weeks.

Mood will be measured by change in score using the following assessment tools at baseline and 20 weeks:
Beck Depression Inventory
Center for Epidemiologic Studies Depression Scale Revised

Quality of Life will be measured by change in score using the following assessment tools at baseline and 20 weeks:
Norfolk Quality of Life Questionnaire
MOS SF-36 Questionnaire

triacylglycerol/atrophy

Effect of Coconut Milk Supplementation to Improve Nutritional Status in Cirrhosis Patient

A Nutritional Intervention for Diabetic Neuropathy (WCCR-DN2)

A Nutritional Intervention for Diabetic Neuropathy

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