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triacylglycerol/oksendamine

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ArtiklidKliinilistes uuringutesPatendid
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[The effect of intragastric balloon on serum lipids level in patients with morbid obesity].

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Obesity is recently considered as the twentieth first century epidemy. An excessive accumulation of adipocytes that constitute metabolically active tissue, plays an important role in lipid and carbohydrate metabolism. In the morbidly obese population dyslipidemia is common. UNASSIGNED To determine

[Leptin levels in female patients with restrictive and purgative types of anorexia nervosa].

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BACKGROUND Anorexia nervosa is an eating disorder with typically chronic course. Two subtypes of anorexia nervosa have been described based on the pattern of eating behavior. Restrictive form of anorexia nervosa is characterized by chronically decreased food intake, while the purgative subtype

Short-term outcomes of the new intragastric balloon End-Ball® for treatment of obesity.

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BACKGROUND Intragastric balloons (IGBs) have been successfully used to treat obesity for the last 18 years. These balloons are made of different materials and filled with either air or saline. It seems that balloons filled with saline result in more effective weight loss, but are associated with

Intestinal Failure and Aberrant Lipid Metabolism in Patients With DGAT1 Deficiency.

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Congenital diarrheal disorders are rare inherited intestinal disorders characterized by intractable, sometimes life-threatening, diarrhea and nutrient malabsorption; some have been associated with mutations in diacylglycerol-acyltransferase 1 (DGAT1), which catalyzes formation of triacylglycerol

Proof of mechanism for the DGAT1 inhibitor AZD7687: results from a first-time-in-human single-dose study.

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OBJECTIVE Inhibition of diacylglycerol acyltransferase 1 (DGAT1), which catalyses the final step in triacylglycerol (TAG) assembly, is suggested as a treatment for type 2 diabetes and obesity based on animal data indicating insulin sensitization and weight reduction. This first-time-in-human single
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