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CLA supplementation and aerobic exercise lower blood triacylglycerol, but have no effect on peak oxygen uptake or cardiorespiratory fatigue thresholds.

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This study examined the effects of 6 weeks of conjugated linoleic acid (CLA) supplementation and moderate aerobic exercise on peak oxygen uptake (VO2 peak), the gas exchange threshold (GET), the respiratory compensation point (RCP), and serum concentrations of cholesterol, triacylglycerol, and

L-Carnitine treatment reduces severity of physical and mental fatigue and increases cognitive functions in centenarians: a randomized and controlled clinical trial.

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BACKGROUND Centenarians are characterized by weakness, decreasing mental health, impaired mobility, and poor endurance. L-Carnitine is an important contributor to cellular energy metabolism. OBJECTIVE This study evaluated the efficacy of L-carnitine on physical and mental fatigue and on cognitive

Walnut extract exhibits anti-fatigue action via improvement of exercise tolerance in mice.

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This study was conducted to investigate the anti-fatigue effect of walnut extract (WE) on forced swimming capacity in mice. Twenty-eight male ICR mice were randomly divided into four groups, a vehicle control (VC) or one of three WE administered groups (300, 600 and 900 mg/kg/day). WE was orally

Mental and physical fatigue-related biochemical alterations.

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OBJECTIVE To confirm fatigue-related biochemical alterations, we measured various parameters just before and after relaxation and fatigue-inducing mental or physical sessions. METHODS Fifty-four healthy volunteers were randomized to perform relaxation and fatigue-inducing mental and physical

Cornu cervi pantotrichum supplementation improves exercise performance and protects against physical fatigue in mice.

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Cornu cervi pantotrichum (CCP) is a well-known yang-invigorating agent used in traditional Chinese medicine that can nourish the blood, tonify qi, and invigorate bones and tendons with multifunctional bioactivities. However, evidence on the effects of CCP on exercise performance and physical fatigue

Changbai Mountain Ginseng (Panax ginseng C.A. Mey) Extract Supplementation Improves Exercise Performance and Energy Utilization and Decreases Fatigue-Associated Parameters in Mice.

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Changbai Mountain Ginseng (CMG, Panax ginseng C.A. Mey) is a traditional medicine commonly found in Northeast China and grows at elevations of 2000 m or higher in the Changbai Mountain Range. CMG, considered to be a "buried treasure medicine", is priced higher than other types of ginseng. However,

Nutritional strategies for promoting fat utilization and delaying the onset of fatigue during prolonged exercise.

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Carbohydrate ingestion before and during endurance exercise delays the onset of fatigue (reduced power output). Therefore, endurance athletes are recommended to ingest diets high in carbohydrate (70% of total energy) during competition and training. However, increasing the availability of plasma

L-ornithine supplementation attenuates physical fatigue in healthy volunteers by modulating lipid and amino acid metabolism.

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We examined the effects of L-ornithine administration on physical fatigue. In a double-blind, placebo-controlled, 2-way crossover study, 17 healthy volunteers were randomized to L-ornithine (2000 mg/d for 7 days and 6000 mg/d for 1 day as L-ornithine hydrochloride) or placebo for 8 days. The

Effect of two breakfasts, different in carbohydrate composition, on hunger and satiety and mood in healthy men.

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OBJECTIVE To study the effect of simple vs complex carbohydrates (SCHO and CCHO respectively) containing breakfasts on blood parameters, hunger and satiety and mood. METHODS A 2-day, open, randomised, cross-over trial. METHODS A total of 26 male subjects (34+/-6 y; BMI 23.4+/-2.2 kg

The regulatory, informational, and immunomodulatory roles of fat fuels.

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Fat oxidation provides a fuel for many tissues and it provides an important signal to decrease glucose utilization and oxidation in muscle and so conserve glucose for essential organs such as the brain. The control of fatty acid oxidation is achieved in part through its plasma concentrations, which

Legal nutritional supplements during a sporting event.

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Nutrition significantly influences sports performance; however, the efficacy of any nutritional supplement or strategy should be carefully considered in relation to the event and the sex, training and nutritional status of the participant. The causes of fatigue, mechanism of action, safety and

Utilization of lipids during exercise in human subjects: metabolic and dietary constraints.

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During endurance exercise, skeletal muscle relies mainly on both carbohydrate (CHO) and fat oxidation to cover energy needs. Numerous scientific studies have shown that increasing the exercise intensity leads to a progressive utilization of CHO. The latter will induce a state of glycogen depletion

Naturally occurring R225W mutation of the gene encoding AMP-activated protein kinase (AMPK)gamma(3) results in increased oxidative capacity and glucose uptake in human primary myotubes.

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OBJECTIVE AMP-activated protein kinase (AMPK) has a broad role in the regulation of glucose and lipid metabolism making it a promising target in the treatment of type 2 diabetes mellitus. We therefore sought to characterise for the first time the effects of chronic AMPK activation on skeletal muscle

Exercise- and metabolism-associated blood variables in Standardbreds fed either a low- or a high-fat diet.

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Feeding a high-fat diet increases fat utilisation and may decrease glycogen utilisation resulting in a lower lactate production during moderate exercise. The effects of fat feeding on exercise- and lipid metabolism-associated blood variables were evaluated in 6 Standardbred horses during submaximal

Symposium: Limits to fat oxidation by skeletal muscle during exercise--introduction.

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Lipids, in the form of adipose tissue triacylglycerol (TG), intramuscular triglyceride (IMTG), and dietary-derived fatty acids (FA) from plasma TG (chylomicrons), and very low-density lipoproteins (VLDL), represent the largest store of nutrient energy in humans. Yet despite the abundance of

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