A pharmaceutical composition for the treatment of rheumatism and a method of preparing it are provided. The composition consists of an alcoholic extract of 1-4 parts by weight Tripterygium hypoglaucum (Levl.) Hutch.; 1-4 parts by weight Epimedium brevicornum Maxim.; 1-4 parts by weight Lycium barbarum L.; and 1-4 parts by weight Cuscuta chinensis Lam., or Cuscuta australis R. Br. The composition has substantial therapeutic efficacy, with mild side effects, and is easy to administer.

Sichuan Institute of Chinese Materia Medica

Guangzhou Chen Li Ji Pharmaceutical Factory

Pharmaceutical composition for treating rheumatism, and method of making same

A Tripterygium wilfordii Hook F preparation having an improved LD.sub.50 in mice, an improved therapeutic activity:toxic index ratio and a lower amount of triptolide as compared to previous preparations is disclosed. The LD.sub.50 in mice of the T. wilfordii preparation is greater than about 860 mg/kg, the therapeutic activity:toxic index ratio is greater than about 2.6.times.10.sup.-3, and the amount of triptolide is less than about 1.3 .mu.g/mg. The preparation is useful for immunosuppression, in particular, the suppression of primary antibody response and suppression of autoimmune disease and for the treatment of rheumatoid arthritis.

tripterygium wilfordii/seenevastane

Pharmaceutical composition for treating rheumatism, and method of making same

Preparations and uses thereof for immunosuppression

Kõige täiuslikum ravimtaimede andmebaas, mida toetab teadus