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visceral pain/atrophy
Link salvestatakse lõikelauale
8 tulemused
An atypical case of SCN9A mutation presenting with global motor delay and a severe pain disorder.
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Logi sisse
BACKGROUND
Erythromelalgia due to heterozygous gain-of-function SCN9A mutations usually presents as a pure sensory-autonomic disorder characterized by recurrent episodes of burning pain and redness of the extremities.
METHODS
We describe a patient with an unusual phenotypic presentation of gross
Neuroimaging Findings in Sepsis-Induced Brain Dysfunction: Association with Clinical and Laboratory Findings.
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Logi sisse
BACKGROUND
Incidence and patterns of brain lesions of sepsis-induced brain dysfunction (SIBD) have been well defined. Our objective was to investigate the associations between neuroimaging features of SIBD patients and well-known neuroinflammation and neurodegeneration factors.
METHODS
In this
Gene expression profiling and endothelin in acute experimental pancreatitis.
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Logi sisse
OBJECTIVE
To analyze gene expression profiles in an experimental pancreatitis and provide functional reversal of hypersensitivity with candidate gene endothelin-1 antagonists.
METHODS
Dibutyltin dichloride (DBTC) is a chemical used as a polyvinyl carbonate stabilizer/catalyzer, biocide in
Capsaicin sensitive-sensory nerves and blood pressure regulation.
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Logi sisse
Capsaicin (8-methyl-N-vannillyl-6-nonenamide), via binding to the vanilloid receptor subtype 1 (VR1), stimulates a subpopulation of primary afferent neurons that project to cardiovascular and renal tissues. These capsaicin-sensitive primary afferent neurons are not only involved in the perception of
Selective 5-hydroxytryptamine antagonism: a role in irritable bowel syndrome and functional dyspepsia?
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Logi sisse
BACKGROUND
Abnormalities of gut motility and visceral pain perception are both thought to be involved in the pathogenesis of irritable bowel syndrome and may be susceptible to modulation by drugs affecting the various 5-HT receptor subtypes. The aim of this study was to investigate the therapeutic
The vanilloid receptor and hypertension.
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Logi sisse
Mammalian transient receptor potential (TRP) channels consist of six related protein sub-families that are involved in a variety of pathophysiological function, and disease development. The TRPV1 channel, a member of the TRPV sub-family, is identified by expression cloning using the "hot"
Cannabinoid receptor 2 agonist attenuates pain related behavior in rats with chronic alcohol/high fat diet induced pancreatitis.
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Logi sisse
BACKGROUND
Chronic Pancreatitis (CP) is a complex and multifactorial syndrome. Many contributing factors result in development of dysfunctional pain in a significant number of patients. Drugs developed to treat a variety of pain states fall short of providing effective analgesia for patients with
Transient receptor potential ankyrin 1 mediates chronic pancreatitis pain in mice.
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Logi sisse
Chronic pancreatitis (CP) is a devastating disease characterized by persistent and uncontrolled abdominal pain. Our lack of understanding is partially due to the lack of experimental models that mimic the human disease and also to the lack of validated behavioral measures of visceral pain. The
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