Acid phosphatase in serum: increase in acute myocardial infarction.

Ten consecutive cases of acute transmural myocardial infarction were accompanied by a rise of 50 to 400 percent in the serum acid phenylphosphatase. The increase in phosphatase began several hours after onset of symptoms and lasted 3 to 5 days. A similar rise was seen during the acute stages of other thromboembolic diseases. While the mechanism by which this acid hyperphenylphosphatasia occurs is not clear, platelets may play an important role.