Collapse and massive pulmonary edema secondary to thrombosis of a mitral mechanical heart valve prosthesis during low-molecular weight heparin therapy.
کلید واژه ها
خلاصه
Mechanical heart valves (MHV) are particularly exposed to thrombosis if anticoagulation becomes ineffective. Thromboembolic complications may be avoided by oral anticoagulation with vitamin K antagonists or derivatives of unfractionated heparin. A few cases of low-molecular weight heparin (LMWH) as sole anticoagulant in patients with MHV have been published, though with contradictory results. We report a case of a massive thrombosis of a St. Jude Medical mitral valve after the patient had been treated for one month with calcium nadroparin (Fraxiparine).