Brain Research 1985-Jul
Combined treatment with muscarinic and nicotinic cholinergic antagonists slows development of kindled seizures.
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خلاصه
Rats were given daily injections of atropine, mecamylamine or both drugs in combination, 1 h prior to daily electrical amygdaloid kindling stimulation. Neither drug was effective alone, but the two drugs in combination significantly increased the latency to develop stage 5 kindled seizures.