[Urinary excretion of Tamm-Horsfall protein, albumin and beta-2 microglobulin in children with recurrent urinary tract infection].

In the study 27 children after urinary tract infection (UTI) and 28 healthy children were examined. Vesico-uretic reflux in 10 patients, and in 17 normal urinary excretion were diagnosed. In 11 children the family history was documented. The 17 healthy controls were siblings of children with normal urinary excretion. In all children urinary excretion of albumin, beta 2-microglobulin and Tamm-Horsfall protein (THP) were examined. Children with UTI both with and without urinary obstruction show the increased urinary excretion of THP as compare with healthy children. Healthy siblings of children with UTI show increased urinary concentration of THP as compared with healthy controls. In both examined groups of children with UTI, function of glomeruli, procimal and distal tubuli measured by urinary excretion of albumin, beta 2-microglobulin and THP were normal.