SARS-CoV-2 virus and liver expression of host receptors: Putative mechanisms of liver involvement in COVID-19.

Zhang et al. showed that COVID-19 affected patients' present liver biochemistry abnormalities, including elevation of aminotransferases, gamma-glutamyl transferase, and alkaline phosphatase ¹ . Hence, several possible clinical scenarios in the setting of liver diseases have been postulated. First, patients with chronic liver disease may be more vulnerable to the severe clinical consequences of COVID-19, including oxygen desaturation and hypoxemia due to severe pneumonia or the cytokine storm ^1;2 . Second, liver biochemistry abnormalities are the consequence of drug toxicity.