A method for diagnosing subacute cardiac dysfunction is performed by electrocardiographically monitoring an ambulatory patient who has persistent unexplainable fatigue and determining the frequency when the T-wave of the ambulatory patient is not positive to determine that subacute myocarditis or a cardiomyopathy is present. This monitoring is preferably performed by a portable monitor and the data is magnetically stored so as to permit subsequent analysis. A treatment is prescribed, preferably restricting activity and refraining from the intake of alcohol as well as antiviral chemotherapy and immunomodulators, when there is an excessively high frequency of the T-wave not being positive. Recovery is determined by further electrocardiographic monitoring of the ambulatory patient and noting when the normally positive T-waves are present all, or at least almost all, of the time.

Diagnosing and treating subacute cardiac dysfunction

The invention relates to new therapeutically active and selective inhibitors of the enzyme dipeptidyl peptidase-IV, pharmaceutical compositions comprising the compounds and the use of such compounds for treating diseases that are associated with proteins that are subject to processing by DPP-IV, such as Type 2 diabetes mellitus, hyperglycemia, impaired glucose tolerance, metabolic syndrome (Syndrome X or insulin resistance syndrome), glucosuria, metabolic acidosis, cataracts, diabetic neuropathy, diabetic nephropathy, diabetic retinopathy, diabetic cardiomyopathy, Type 1 diabetes, obesity, conditions exacerbated by obesity, hypertension, hyperlipidemia, atherosclerosis, osteoporosis, osteopenia, frailty, bone loss, bone fracture, acute coronary syndrome, infertility due to polycystic ovary syndrome, short bowel syndrome, anxiety, depression, insomnia, chronic fatigue, epilepsy, eating disorders, chronic pain, alcohol addiction, diseases associated with intestinal motility, ulcers, irritable bowel syndrome, inflammatory bowel syndrome and to prevent disease progression in Type 2 diabetes. The invention also relates to a method of identifying an insulin secretagogue agent for diabetes.

cardiomyopathies/خستگی پزشکی

Diagnosing and treating subacute cardiac dysfunction

Fluorinated cyclic amides as dipeptidyl peptidase IV inhibitors

کاملترین پایگاه داده گیاهان دارویی با پشتیبانی علمی