صفحه 1 از جانب 31 نتایج
BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to novel anthranilic acid derivatives exhibiting an extremely strong antiallergic activity when administered orally to mammals including human beings. More particularly, this invention relates to anthranilic acid
BACKGROUND OF THE INVENTION
The present invention is novel compounds which are 4,6-di-tertiary-butyl-5-hydroxy-1,3-pyrimidine substituted 1,2,4- and 1,3,4-thiadazoles and oxadiazoles, and 1,2,4-triazoles, and pharmaceutically acceptable acid addition or base salts thereof, pharmaceutical
BACKGROUND OF THE INVENTION
This invention relates to 3-hydroxyazabenzothiophenes having the 2-position substituted with an optionally substituted aryl, aralkyl, alkyl, or alkenyl group, for example, 3-acetyloxy-7-aza-2-phenyl-benzo[b]thiophene.
These novel azabenzothiophenes are found to be either
BACKGROUND OF THE INVENTION
This invention relates to 3-hydroxyazabenzothiophenes having the 2-position substituted with an optionally substituted aryl, aralkyl, alkyl, or alkenyl group, for example, 3-acetyloxy-7-aza-2-phenyl-benzo[b]thiophene.
These novel azabenzothiophenes are found to be either
The present invention relates to 2-amino-5-oxo-5 H-[1]benzopyrano[2,3-b]pyridine-3-carboxylic acid derivatives of the formula (I): ##STR3## wherein A is ##STR4## (R, R.sup.1 and R.sup.2 are independently hydrogen or lower alkyl and m is 0 or 1, with the proviso that when m is 1, R.sup.1 is hydrogen)
BACKGROUND OF THE INVENTION
This invention relates to 3-hydroxyazabenzothiophenes having the 2-position substituted with an optionally substituted aryl, aralkyl, alkyl, or alkenyl group, for example, 3-acetyloxy-7-aza-2-phenyl-benzo[b]thiophene.
These novel azabenzothiophenes are found to be either
This invention relates to certain novel 3-nitrocoumarin derivatives, to a method for their preparation, to pharmaceutical compositions comprising such compounds and to their use in the treatment of certain allergic conditions.
It is known that some types of cells are activated by certain
BACKGROUND OF THE INVENTION
Mast cells are major effector cells for immediate hypersensitivity and allergic diseases. In these settings, mast cell activation by IgE antibody and antigen contributes to pathology, such as in anaphylaxis, asthma, hay fever and atopic dermatitis or eczema. Activation of
BACKGROUND OF THE INVENTION
1. Technical Field
The present invention relates to a nitrogen-containing tricyclic compound useful as a medicine, a medicine containing the same and processes for producing the same. More particularly, it relates to a novel nitrogen-containing tricyclic compound useful
BACKGROUND OF THE INVENTION
1. Technical Field
The present invention relates to a nitrogen-containing tricyclic compound useful as a medicine, a medicine containing the same and processes for producing the same. More particularly, it relates to a novel nitrogen-containing tricyclic compound useful
BACKGROUND OF THE INVENTION
1. Technical Field
The present invention relates to a nitrogen-containing tricyclic compound useful as a medicine, a medicine containing the same and processes for producing the same. More particularly, it relates to a novel nitrogen-containing tricyclic compound useful
BACKGROUND OF THE INVENTION
This invention relates to nuclear-substituted cinnamoylaminobenzoic acid and hydrocinnamoylaminobenzoic acid derivatives exhibiting a strong antiallergic action when administered orally to mammalia including humans and to methods and compositions for using the same.
Up to
FIELD OF THE INVENTION
The present invention relates to a heterocyclic ring condensed benzothiazine compound useful as a medicament, a medicament containing the same and processes for producing the same. More specifically, it relates to a novel heterocyclic ring condensed benzothiazine compound
This is a continuation in-part of PCT/JP90/00905, filed Jul. 12, 1990.
FIELD OF THE INVENTION
The present invention relates to a novel styryl compound, a pharmaceutically acceptable salt thereof or an ester thereof which possesses leukotriene-antagonistic actions and inhibitory actions against
BACKGROUND OF THE INVENTION
The present invention is novel compounds which are 4,6-di-tertiary-butyl-5-hydroxy-1, 3-pyrimidine substituted 1,2,4- and 1,3,4-thiadazoles and oxadiazoles, and 1,2,4-triazoles, and pharmaceutically acceptable acid addition or base salts thereof, pharmaceutical