صفحه 1 از جانب 403 نتایج
TECHNICAL FIELD
Methods of treating developmental disorders and/or seizure disorders with etifoxine are provided.
BACKGROUND
Treatments for developmental disorders such as Autistic Spectrum Disorder, Dravet syndrome, Rett syndrome, Angelman syndrome, Fragile X syndrome, and Fragile X-associated
FIELD OF THE INVENTION
The present invention relates to bridged dianilino compounds and pharmaceutical compositions and method of use thereof for the prevention and treatment of epilepsies, seizures, and other electroconvulsive disorders. Specifically, this invention relates to the use of
BACKGROUND OF THE INVENTION
This invention was made with Government support under contract AI47822 and GM37734. The government has certain rights in this invention.
A seizure is a paroxysmal event due to abnormal, excessive, hypersynchronous discharges from an aggregate of central nervous system
BACKGROUND OF THE INVENTION
A seizure is a paroxysmal event due to abnormal, excessive, hypersynchronous discharges from an aggregate of central nervous system (CNS) neurons, while epilepsy is a condition in which a person has recurrent seizures due to a chronic, underlying process. Experimental and
FIELD OF THE INVENTION
The present invention relates to the use of agmatine and analogs thereof in the prevention and treatment of epilepsies, seizures, and other electroconvulsive disorders.
BACKGROUND OF THE INVENTION
Epilepsy is a general term describing brain disorders that are characterized by
TECHNICAL FIELD
Methods of treating seizure disorders are provided.
BACKGROUND
Seizure disorders typically involve abnormal nerve cell activity in the brain, causing seizures which may be manifested by periods of unusual behavior, sensations, diminished consciousness and sometimes loss of
BACKGROUND OF THE INVENTION
1. Field of Invention
This invention relates to treatment of human beings for conditions associated with deficiencies in the N-6-trimethyl-L-lysine (TML) pathway affecting biosynthesis of carnitine. Such conditions include: (1) seizures, myoclonic seizures, epilepsy,
BACKGROUND OF THE INVENTION
Epileptic disorders affect about 20 to 40 million people worldwide. Generalized idiopathic epilepsies (IGE) cause 40% of all epileptic disorders and commonly have a genetic basis (Plouin, 1994). Most of the IGEs that are inherited are complex, non-monogenic diseases. One
BACKGROUND OF THE INVENTION
Epileptic disorders affect about 20 to 40 million people worldwide. Generalized idiopathic epilepsies (IGE) cause 40% of all epileptic disorders and commonly have a genetic basis (Plouin, 1994). Most of the IGEs that are inherited are complex, non-monogenic diseases. One
Gamma-aminobutyric acid (GABA) is a major inhibitory neurotransmitter of the CNS. Various theories have been advanced to implicate deficiencies in GABA-mediated neuronal inhibition as a contributing factor in the pathogenesis of seizure disorders, such as epilepsy. In laboratory animals, a decrease
Gamma-aminobutyric acid (GABA) is a major inhibitory neurotransmitter of the CNS. Various theories have been advanced to implicate deficiencies in GABA-mediated neuronal inhibition as a contributing factor in the pathogenesis of seizure disorders, such as epilepsy. In laboratory animals, a decrease
BACKGROUND OF THE INVENTION
Epilepsy, a complex neurological disorder estimated to affect over 50 million people worldwide, is characterized by recurrent spontaneous seizures due to neuronal hyperexcitability and hypersynchronous neuronal firing. Despite the availability of more than 20
TECHNICAL FIELD
The disclosure relates to patient monitoring, and, more particularly, to collecting information to evaluate a patient condition.
BACKGROUND
Some neurological disorders, such as epilepsy, are characterized by the occurrence of seizures. Seizures may be attributable to abnormal
BACKGROUND OF THE INVENTION
The present invention relates to an apparatus and method for detecting an epilepsy seizure.
A brain wave is obtained by measuring a change in potential difference caused by a weak electrical activity of the brain by means of scalp electrodes or intracranial electrodes or
This application claims the priority benefit under 35 U.S.C. .sctn.119 of Japanese Patent Application No. 2012-0067709 (filed on Mar. 23, 2012), which is hereby incorporated in its entirety by reference.
BACKGROUND OF THE INVENTION
The present invention relates to an apparatus and method for