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Histological study of pancreatic beta-cell loss in relation to the insulitis process in the non-obese diabetic mouse.

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Non-obese diabetic (NOD) mice spontaneously develop an autoimmune diabetes with higher incidence in females than in males. In order to elucidate possible factors involved in the different incidence of diabetes between male and female mice, we studied the progression of pancreatic beta-cell loss in

Tautomerase Activity-Lacking of the Macrophage Migration Inhibitory Factor Alleviates the Inflammation and Insulin Tolerance in High Fat Diet-Induced Obese Mice.

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Macrophage migration inhibitory factor (MIF) has multiple intrinsic enzymatic activities of the dopachrome/phenylpyruvate tautomerase and thiol protein oxidoreductase, and plays an important role in the development of obesity as a pro-inflammatory cytokine. However, which enzymatic activity of MIF

Hepcidin and iron metabolism in non-diabetic obese and type 2 diabetic rats.

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The aim of this study was to investigate the changes of iron levels and hepatic regulatory molecules expression involved in iron metabolism in non-diabetic obese/type 2 diabetic rat models. Male Wistar rats were divided into 3 groups: control group, non-diabetic obese group and type 2 diabetic group

Occurrence and significance of Mallory bodies in morbidly obese patients. An immunohistochemical study.

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Liver biopsies from 61 consecutive patients with morbid obesity (less than 60% overweight) and from 48 patients with alcoholic liver disease were examined for the presence of Mallory bodies. For the detection both routine haematoxylin and eosin stained sections and sections exposed to an

A histomorphometric study on the hepatoprotective effects of a green rooibos extract in a diet-induced obese rat model.

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Obesity, type two diabetes mellitus and insulin resistance are associated with increased oxidative stress and inflammation. Unfermented green rooibos is an aspalathin rich variant of traditional fermented rooibos (Aspalathus linearis) and has a high polyphenol content. The present study aimed to

Atherosclerosis in relation to fat penniculus (obesity) between xiphoid and umbilicus.

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BACKGROUND It has been shown that possible influence of body weight is more evident for coronary than aortic atherosclerosis; and more in men than women. Coronary heart disease due to obesity in males becomes significant when body mass index (BMI) exceeds 30 (30% overweight) and does not affect the

Histology of adipose tissue inflammation in Dercum's disease, obesity and normal weight controls: a case control study.

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BACKGROUND Dercum's disease (DD) is characterised by obesity and chronic pain (> 3 months) in the adipose tissue. The pathogenesis of DD is unknown, but inflammatory components have been proposed. In previous reports and studies, an inconsistent picture of the histological appearance of the adipose

Protective effects of saffron extract and crocin supplementation on fatty liver tissue of high-fat diet-induced obese rats.

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BACKGROUND Saffron is the dried stigma of Crocus sativus L. flower which commonly used as a natural remedy to enhance health and even fights disease in the Middle-East and Southeast Asian countries. METHODS This study was aimed to investigate protective effect of saffron extract and crocin in fatty

Multigenerational obesity-induced perturbations in oocyte-secreted factor signalling can be ameliorated by exercise and nicotinamide mononucleotide.

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Can maternal and offspring high-fat diet (HFD)-induced changes in mRNA expression levels in mice be ameliorated by interventions in female offspring?Our results indicate that exercise and nicotinamide mononucleotide (NMN) can ameliorate the negative effects

Eicosapentaenoic acid/docosahexaenoic acid 1:1 ratio improves histological alterations in obese rats with metabolic syndrome.

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BACKGROUND Marine polyunsaturated fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have been associated with improvement in the Metabolic Syndrome (MS). The aim of this study is to evaluate how three fish-oil diets with different eicosapentaenoic acid/docosahexaenoic acid

Splenocytes from non-obese-diabetic mice binding to xenogeneic beta-cells in vitro: an early marker of cell-mediated immunity.

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In as much as Type 1 diabetes is a T-cell mediated autoimmune disease, the valuation of cell mediated immunity would be useful for the study of its prodromal period. We have previously reported an increased binding of T splenocytes with alpha beta receptors from NOD mice to xenogeneic rat insulinoma

[Lipoemulsification. A histological study on the action of ultrasound, access site and adipose tissue].

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A new mini-invasive technique for the lysis of subcutaneous adipose tissue has emerged in recent years. This directly applies ultrasounds to the tissue by titanium probes. Ultrasounds act on parenchyma tissues, saving the structure and integrity of the blood vessels. Our study show histological

Histopathological changes in the islets of Langerhans in scrapie 139H-affected hamsters.

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Previous studies showed that the 139H strain of scrapie injected into hamsters caused obesity, a marked hypertrophy of the islets of Langerhans, generalized endocrinopathy and marked hypoglycaemia-hyperinsulinaemia. In the current study, female weanling Syrian hamsters (LVG/LAK strain) were

ApoA-1 infusion reduces arterial cholesterol and myocardial lesions in a rat model of cardiac dysfunction and insulin resistance.

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OBJECTIVE Low plasma high-density lipoprotein cholesterol (HDL-C) concentration is associated with the metabolic syndrome (MetS) and increased prevalence of cardiovascular disease (CVD). Animal and human studies report infusion of apolipoprotein A-1 (apoA-1) can reduce endothelial dysfunction,

Clinical and histopathological characteristics in patients with scarring folliculitis type of acne inversa.

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Objective: This study was designed to study the clinical and histopathological characteristics of patients with the scarring folliculitis type acne inversa in Chinese population. Methods: A total of 21 patients with acne inversa and 6 controls without known dermatological disease were recruited from

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Herbal & Natural Medicine

کاملترین پایگاه داده گیاهان دارویی با پشتیبانی علمی

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