صفحه 1 از جانب 68 نتایج
TECHNICAL FIELD
The present invention relates to compositions and associated methods for suppression of primary tumor growth and metastasis by use of sulfated, super-sulfated non-anticoagulant low and ultra-low molecular weight heparins, and their nanoformulations.
BACKGROUND
The Glycosaminoglycans
The present invention relates to active agents having anti-tumour and/or anti-tumourigenic activity, pharmaceutical compositions of these agents and the pharmaceutical uses of such agents and compositions. The invention also relates to in vitro methods of screening agents for anti-tumour and/or
BACKGROUND OF THE INVENTION
Field of the Invention
This invention generally relates to a coating having heparin attached thereto on an implantable device, such as a stent.
Description of the Background
Blood has a property of being coagulated by the action of various components in blood when it has
FIELD OF THE INVENTION
This invention relates to O-desulfated heparin compositions and methods of making the same, preferably 6-O-desulfated heparin compositions, wherein the methods permit regulating the degree of 6-O-desulfation. The compositions are useful for treating various diseases, including
FIELD OF THE INVENTION
This invention relates to methods of making O-desulfated heparin compositions, preferably 2-O, 3-O desulfated heparin compositions, wherein the methods permit regulating the degree of 2-O, 3-O desulfation to produce compositions that can be variably desulfated including about
BACKGROUND OF THE INVENTION
Heparin and other naturally occurring glycosaminoglycans, such as dermatan sulfate or heparan sulfate, possess medically useful properties. Recently, several low molecular weight heparins from various chemical or enzymatic alepolymerization processes have been developed
BACKGROUND OF THE INVENTION
1. Field of the Invention
The invention in the field of biochemistry and neurosciences relates to compositions and methods based on the neuregulin heparin binding domain (N-HBD) use to target other polypeptides to cell surfaces and extracellular matrix rich in heparan
REFERENCE TO A SEQUENCE LISTING SUBMITTED VIA EFS-WEB
The content of the ASCII text file of the sequence listing named "20110311.sub.--034044.sub.--083WO1_ST25" which is 17.6 kb in size was created on 11 Mar. 2011 and electronically submitted via EFS-Web herewith the application is incorporated
FIELD OF THE INVENTION
This invention relates to methods of making O-desulfated heparin compositions, preferably 2-O, 3-O desulfated heparin compositions, wherein the methods permit regulating the degree of 2-O, 3-O desulfation to produce compositions that can be variably desulfated including about
FIELD OF THE INVENTION
This invention relates to methods of making O-desulfated heparin compositions, preferably 2-O, 3-O desulfated heparin compositions, wherein the methods permit regulating the degree of 2-O, 3-O desulfation to produce compositions that can be variably desulfated including about
CROSS-REFERENCE TO RELATED APPLICATIONS
This application claims the benefit under 35 USC 119(a) of Korean Patent Application No. 10-2012-0112111 filed on Oct. 9, 2013, in the Korean Intellectual Property Office, the entire disclosure of which is incorporated herein by reference for all
BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention generally relates to a prodrug formed of heparin and a drug and drug-delivery stents formed from a material having the prodrug.
2. Description of the Background
Blood has a property of being coagulated by the action of various
FIELD OF THE INVENTION
This invention generally relates to a prodrug formed of heparin and a drug and drug-delivery stents formed from a material having the prodrug.
DESCRIPTION OF THE BACKGROUND
Blood has a property of being coagulated by the action of various components in blood when it has come
BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention generally relates to a prodrug formed of heparin and a drug and drug-delivery stents formed from a material having the prodrug.
2. Description of the Background
Blood has a property of being coagulated by the action of various
FIELD OF THE INVENTION
This invention generally relates to a prodrug formed of heparin and a drug and drug-delivery stents formed from a material having the prodrug.
DESCRIPTION OF THE BACKGROUND
Blood has a property of being coagulated by the action of various components in blood when it has come