pancytopenia/خستگی پزشکی

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[Copper deficiency with pancytopenia, bradycardia and neurologic symptoms].

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A 48-year-old man was referred to our hospital in December, 2005 because of general fatigue, gait disturbance and bradycardia. He had a history of polysurgery due to recurrent ileus and had been treated with home total parenteral nutrition for the short-bowel syndrome since 2003. Clinical findings

Graves' disease causing pancytopenia and autoimmune hemolytic anemia at different time intervals: a case report and a review of the literature.

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Graves' disease (GD) is associated with various hematologic abnormalities but pancytopenia and autoimmune hemolytic anemia (AIHA) are reported very rarely. Herein, we report a patient with GD who had both of these rare complications at different time intervals, along with a review of the related

An unusual cause of pancytopenia: Whipple's disease.

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Whipple's disease is a systemic infectious disease caused by the bacteria Tropheryma whipplei. The most common clinical manifestations of Whipple's disease are weight loss (92%), hypoalbuminemia and steatorrhea (91%, respectively), diarrhea (72%), arthralgia (67%), and abdominal pain (55%).

Anorexia nervosa-associated pancytopenia mimicking idiopathic aplastic anemia: a case report.

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BACKGROUND Patients with anorexia nervosa (AN) often present with pancytopenia. In most cases described in the literature, AN with pancytopenia demonstrates gelatinous marrow transformation (GMT), which is a typical bone marrow feature of malnutrition. Differentiation of AN-associated pancytopenia

[Pancytopenia and hemolysis--diagnosis, differential diagnosis and therapy of pernicious anemia].

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Pernicious anemia and Vitamin B12 deficiency have a wide range of symptoms and are a common finding in the elderly. A 73 year old female is admitted to the hospital because of dyspnea, fatigue and loss of appetite and weight. While previous medical history and physical examination are inconspicuous,

[Clinical reasoning and decision-making in practice. A young boy with fever, pancytopenia and an enlarged spleen].

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A 5-year-old boy presented with fever and fatigue after a holiday in northern Italy. On physical examination a marked splenomegaly was found. Laboratory investigations showed a pancytopenia as well as several markers suggesting an autoimmune disease. The splenomegaly and pancytopenia continued to

Pancytopenia in two national ethnic groups of Baluchistan.

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BACKGROUND Pancytopenia is a recognisable haematological problem with common categorises diagnosis but best possible diagnostic approach is still to be defined. OBJECTIVE The aim of this study was to determine the frequent causes and clinical presentation of pancytopenia in relation to age and sex

[Pancytopenia, Hemolytic Anemia and Schizocytes: a Pragmatic Approach].

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A 58 year old woman presents with a progressive fatigue and dyspnea associated with paresthesia. Laboratory tests show pancytopenia with hypersegmented neutrophiles, macrocytic hyporegenerative anemia and arguments for hemolysis, in particular highly increased LDH. This constellation strongly

Hormones and the bone marrow: panhypopituitarism and pancytopenia in a man with a pituitary adenoma.

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In rare cases, pancytopenia results from hormonal deficiencies that arise in the setting of panhypopituitarism. Here we describe the unusual case of a 60-year-old man who presented with progressive fatigue and polyuria, and whose laboratory workup revealed a deficiency of the five hormones

Pancytopenia in Multiple Myeloma- An Enigma: Our Experience from Tertiary Care Hospital.

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BACKGROUND Multiple myeloma is a plasma cell neoplasm that is characterized by clonal proliferation of malignant plasma cell in the bone marrow along with M-protein in the serum and/or urine. Pancytopenia as a initial presentation of multiple myeloma is quite unusual. We are presenting a case series

[Pancytopenia, haemolytic anaemia, schistocytes: a frequent pathology mimicking a rare and serious pathology].

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A 83 years old woman presents to our hospital with fatigue and dyspnea since 2 weeks, followed by a painless icterus. On laboratory we discover a pancytopenia with severe haemolytic anaemia, thrombopenia and schistocytosis. This association suggest a thrombotic microangiopathy. In the presence of

[A case of systemic lupus erythematosus presenting with myelofibrosis as a cause of pancytopenia].

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A 54 year-old woman who had a 6 month history of polyarthralgias, oral ulcers, weight loss and fatigue was admitted to the Urawa Municipal Hospital. She developed high fever, dyspnea and thrombocytopenia. Chest radiograph revealed massive right pleural effusion. At this time, laboratory

Pancytopenia after low dose methotrexate therapy in a hemodialysis patient: case report and review of literature.

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Methotrexate (MTX) is widely used in the treatment of rheumatoid arthritis (RA) with a side effect of pancytopenia. However, only a few cases of severe pancytopenia caused by low-dose MTX therapy have been reported, and the condition is rarely reported in uremic patients on dialysis therapy. We

Pancytopenia, including macrocytic anemia, associated with leflunomide in a rheumatoid arthritis patient.

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A female rheumatoid arthritis patient was admitted for productive cough and general fatigue that had gradually developed after leflunomide therapy. Side effects including severe hypoxia, thrombocytopenia, lymphocytopenia, and macrocytic anemia with schistocytes (probably drug-induced megaloblastic

Hairy cell leukemia: clinical, pathological and ultrastructural findings in Asian-Indians.

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BACKGROUND Hairy-cell leukemia (HCL), lymphoproliferative disease of older age, is characterized by projections from surface of abnormal cells. OBJECTIVE The aim was to study the clinical presentation and ultrastructural changes in hairy cells (HCs) following cladribine treatment. METHODS Clinical

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