Iontophoretic Treatment of Hyperkeratosis with Sodium Salicylate.

Ten patients having hyperkeratosis with moderate to severe fissures on palms and soles were treated with iontophoresis using 5-10% aqueous solution of sodium salicylate. The results were excellent within a period of 3-4 weeks (6-8 sittings each for a period of 10-15 minutes). The treatment was free from the problems of salicylism. Follow-up in some of the reclcitrant cases for 4 months after stop the treatment and with no local application, showed neither any relapse nor deterioration. Sodium salicylate iontophoresis in hyperkeratosis seems to be safe well tolerated and far more effective than the usual local applications of salicylic acid.