American Journal of Obstetrics and Gynecology 1979-Feb
Remission of uterine leiomyosarcomas treated with vincristine, Adriamycin, and dimethyl-triazeno-imidazole carboximide.
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Six patients with metastatic uterine leiomyosarcoma have been treated with the combination of vincristine, Adriamycin, and DTIC. Complete remissions were obtained in three patients and a partial remission in a fourth. The average duration of response was 15.6 months and one patient is free of disease at 24 months. Severe nausea and vomiting caused discontinuance of chemotherapy in two patients.
