Two novel thiophenes from Echinops grijissi Hance.

Two novel thiophenes, grijisyne A (1), and grijisone A (2), were isolated from the crude ethanolic extract of the roots of Echinops grijissi Hance. Their structures were determined by spectral methods, especially 2D NMR spectra. All the isolated compounds were tested for their anti-tumor activities against three human tumor cell lines, HL-60, K562, and MCF-7.