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antiarrhythmic/kuume

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[Antiarrhythmic therapy in extreme conditions of artificial whole-body hyperthermia and artificial hyperglycemia in cancer patients].

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It has been shown that sessions of total body hyperthermia (rectal temperature - 40.0-41.8 degrees C) and artificial hyperglycemia (22-23 mmol/l) in combination with chemotherapy in cancer patients with severe cardiac arrhythmias should follow antiarrhythmic pretreatment and should be accompanied by

In vitro antiarrhythmic effect of prior whole body hyperthermia: implication of catalase.

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The protective effect of heat stress against mechanical dysfunction and myocardial necrosis after prolonged ischemia is well known. We have investigated whether the protective effect of heat stress extends to reperfusion arrhythmias in the isolated perfused rat heart. Rats were exposed to 20 min of

Brugada syndrome unmasked by fever: a comprehensive review of literature

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Background: The Brugada pattern is identified on the EKG by a coved ST-segment elevation accompanied by a negative T wave in the early precordial leads in the absence of a cardiac structural abnormality. Brugada pattern and Brugada

Hyperthermia Influences the Effects of Sodium Channel Blocking Drugs in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

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BACKGROUND Fever can increase the susceptibility to supraventricular and ventricular arrhythmias, in which sodium channel dysfunction has been implicated. Whether fever influences the efficacy of sodium channel blocking drugs is unknown. The current study was designed to investigate the temperature

Antiarrhythmic efficacy of ethmozine in patients with ventricular tachycardia as determined by programmed electrical stimulation.

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The antiarrhythmic properties of ethmozine were studied in 27 patients with a history of a cardiac arrest or symptomatic ventricular tachycardia. Programmed electrical stimulation studies were performed in 20 men and seven women with a mean age of 62 years and a mean left ventricular ejection

Procainamide-induced postoperative pyrexia.

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Procainamide is an effective antiarrhythmic that is often used to convert atrial fibrillation to normal sinus rhythm. A side effect of procainamide, rarely reported in the surgical literature, is pyrexia. The pyrexia is a manifestation of an allergic response to this medication. If unrecognized,

Case report: fatal ventricular tachycardia exacerbated by fever in a child.

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Primary ventricular tachycardia (VT) is rare in children. We report a child with VT exacerbated by fever which was ultimately fatal. His first episode occurred at 5 months old and recurred with fever, occasionally causing syncope. Episodes were difficult to control with antiarrhythmic agents during

Propafenone-induced drug fever in the absence of agranulocytosis.

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Propafenone is an antiarrhythmic drug used in the treatment of life-threatening ventricular tachyarrhythmias. Adverse reactions necessitating discontinuation of the medication are common. Propafenone-induced drug fever has not been definitively proven. We present a case report of drug fever

PYREXIA-INDUCED BRUGADA PHENOCOPY.

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Brugada syndrome (BS) is characterized by a typical electrocardiographic (ECG) pattern in the right precordial leads and a predisposition to develop ventricular arrhythmias. Mutations in a subunit of cardiac sodium channel (SCN5A) have been linked to BS. Experimental studies in the literature

Agranulocytosis from antiarrhythmic agents. What to watch for when a medication is first prescribed.

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Anyone who prescribes antiarrhythmic medications should strongly consider monitoring patients for the first 3 months of its use. If agranulocytosis is going to develop, it almost always does so in that period. A complete blood cell count every 1 to 2 weeks can detect neutropenia before symptoms and

Noneffectiveness of verapamil in preventing halothane-induced malignant hyperthermia in susceptible swine.

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Pietrain pigs susceptible to malignant hyperthermia (MH; porcine stress syndrome) were treated with the slow-channel calcium blocker verapamil and then subjected to halothane testing. There was no significant delay in the onset of MH among pigs (3 groups) given different doses of verapamil (1, 5,

Poisoning due to class IA antiarrhythmic drugs. Quinidine, procainamide and disopyramide.

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Quinidine, procainamide and disopyramide are antiarrhythmic drugs in the class 1A category. These drugs have a low toxic to therapeutic ratio, and their use is associated with a number of serious adverse effects during long term therapy and life-threatening sequelae following acute overdose. Class

Clinical organ toxicity of antiarrhythmic compounds: ocular and pulmonary manifestations.

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The history of antiarrhythmic therapy reveals these agents to be associated with a high incidence of toxicity. Although several agents have ocular effects, amiodarone is the most widely recognized for producing adverse effects in the eyes. Corneal microdeposits are almost ubiquitous in patients
BACKGROUND Dantrolene, a specific agent for the treatment of malignant hyperthermia, was found to inhibit Ca(2+) leak through not only the skeletal ryanodine receptor (RyR1), but also the cardiac ryanodine receptor (RyR2) by correcting the defective inter-domain interaction between N-terminal (1-619
Despite tremendous efforts toward developing novel near-infrared (NIR)-absorbing nanomaterials, improvement in therapeutic efficiency remains a formidable challenge in photothermal cancer therapy. This study aims to synthesize a specific peptide conjugated polydopamine-modified reduced graphene
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