Nutrition Related Cancer

Aging

Chocolate

Effects of Chocolate Consumption in Elderly Patients With Cancer in Palliative Care

Effects of Chocolate Consumption in the Nutritional State, Quality of Life, Body Composition, Oxidative Stress and Inflammatory Activity in Elderly Patients With Cancer in Palliative Care

Evaluation by Mini Nutritional Assessment, by the 24-hour Recall Survey, and by the Food Frequency Questionnaire at the basal moment and after 4 weeks of intervention.

Evaluation of ingestion by the 24-hour Recall Survey and by the Food Frequency Questionnaire at the basal moment and after 4 weeks of intervention.

Body composition was evaluated by the deuterium oxide method at the basal moment and after 4 weeks.

The European Organization for Cancer Research and Treatment Questionnaire was administered before and after the intervention of 4 weeks.

The antioxidant capacity was evaluated by the quantification of reduced glutathione and ascorbic acid. Serum lipid peroxidation was measured by determining malonaldehyde levels and the presence and quantification of damage to genetic material by 8-hydroxy-2'-deoxyguanosine levels. All measurements were performed before and after 4 weeks of intervention.

Inflammatory status was evaluated by serum Interleukin 6 levels and C Reactive Protein evaluated before and after the intervention.

Nereida Kilza da Costa Lima

Associate Professor

University of Sao Paulo

Comparative, randomized, non-blind intervention study

Argicolina is a dietary supplement containing monacolin (sachets)

Normolip is a dietary supplement containing monacolin (tablets)

Hypercholesterolemia

Argicolina

Normolip

LDL-cholesterol Lowering Effect of a New Dietary Supplement

LDL-cholesterol Lowering Effect of a New Dietary Supplement. An Open-label, Controlled, Randomized, Cross-over Clinical Trial in Patients With Mild-to-moderate Hypercholesterolemia .

The primary efficacy variable was the LDL-C change between the start and the end (8 weeks)of each treatment period, expressed as a percentage of the initial value

The secondary efficacy variables were the HDL-C changes between the start and the end (8 weeks)of each treatment period, expressed as a percentage of the initial value

The secondary efficacy variables were the Triglycerides between the start and the end (8 weeks)of each treatment period, expressed as a percentage of the initial value

The secondary efficacy variables were the HDL-C between the start and the end (8 weeks)of each treatment period, expressed as a percentage of the initial value

Ispharm srl

Intervention: Twice-daily administration of N-acetyl cysteine 600 mg, VitE 250 IU, VitC 500 mg tablets

Intervention: Twice daily administration of sham/placebo tablet

Migraine, Headaches

N-acetyl cysteine 600 mg, VitE 250 IU, VitC 500 mg tablet

Effect on Migraine Frequency of Combined Anti-oxidant Therapy: The MIGRANT Study.

Effect on Migraine Frequency of Combined Anti-oxidant Therapy: N-acetylcysteine, Vitamin E and Vitamin C (NEC): The MIGRANT Study

Difference in mean number of migraine episodes per month between baseline and final four weeks of the study, for both study groups.

Difference in mean migraine duration (hours) per month between baseline and final four weeks of the study, for both study groups

Difference in mean migraine severity score per month (categorical scale; 0 = nil, 1 = mild, 2 = moderate, 3 = severe) between baseline and final four weeks of the study, for both study groups.

Migraine Disability Assessment Score (MIDAS).

Difference in mean MSQ score per month between baseline and final four weeks of the study, for both study groups. Migraine Specific Quality of Life Questionnaire (MSQ, Version 2.1) score.

Difference in mean HRQOL score per month between baseline and final four weeks of the study, for both study groups.Health Related Quality of Life (HRQOL) score

Number of treatment adverse events per month

Difference in mean number of migraine days per month between baseline and final four weeks of the study, for both study groups.

Responder rate: Percentage of subjects reporting ≥ 30% reduction in migraine episodes per month between baseline and final four weeks of the study, for both study groups

ascorbic acid/karies

Effects of Chocolate Consumption in Elderly Patients With Cancer in Palliative Care

LDL-cholesterol Lowering Effect of a New Dietary Supplement

Effect on Migraine Frequency of Combined Anti-oxidant Therapy: The MIGRANT Study.

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