the intervention groups will receive daily oral nutrition supplement (ONS) enriched in eicosapentaenoic acid, gamma-linolenic acid and antioxidants. The composition of one can (8 fl oz) of the intervention-ONS includes: 14.8 g protein, 22.2 g fat, 25 g carbohydrate, 355 kcal, 1.1 g EPA, 450 mg DHA, 950 mg GLA, 2840 IU vitamin A as 1.2 mg β-carotene, 205 mg Vitamin C, 75 IU vitamin E, 18 ug Selenium, and 5.7 mg Zinc.

iso-caloric -isonitrogenous product (by the same manufacture) and served in cans with the same color and shape.

COVID-19

the intervention group will receive a commercially available anti-inflammatory/antioxidant ONS, which will be given to patients with COVID-19 in the morning 3 hours after breakfast.

oral nutrition supplement (ONS) enriched in eicosapentaenoic acid, gamma-linolenic acid and antioxidants

The placebo group will receive an isocaloric/isonutrigenous ONS at the same time in the same shape/size/color of the cans.

isocaloric/isonutrigenous ONS

Immunonutrition: Interactions of Diet, Genetics, and Inflammation - Google Books. In Immunonutrition: Interactions of Diet, Genetics, and Inflammation

COVID-19: consider cytokine storm syndromes and immunosuppression

Anti-inflammatory/Antioxidant Oral Nutrition Supplementation in COVID-19

Anti-inflammatory/Antioxidant Oral Nutrition Supplementation on the Cytokine Storm and Progression of COVID-19: A Randomized Controlled Trial

Changes in scores of the NRS-2002 for patients with COVID-19 at the end of the study, from 0 to 7 scores, with those scores < 3 means no risk of malnutrition and >= 3 means malnutrition.

Change in serum ferritin at the end of the trial as ferritin is considered as a COVID-19 fatality predictor.

Change in IL-6 at the end of the trial as it represent the cytokine storm and it is considered as a COVID-19 fatality predictor

Change in C-reactive protein in the serum at the end of the trial which reflect the acute phase

Change in the TNF a in the serum at the end of study as it represent severity of the cytokine storm

plasma MCP-1 represent severity of the cytokine storm

Claculation of BMI according to weight / square Height

). The mid-arm muscle area (MAMA) will be calculated according to the following equation: {MAMA= (MAC - π x TSF)2 / 4π}.

changes in the percentage of peripheral O2 saturation by an oximeter

changes in the degree of body temperature by infrared thermometer

change in the count from complete blood counts

change in the rations calculated by division of the neutrophil count by the lymphocyte count

all IPD that underlie results in a publication will be shared

Mahmoud Abulmeaty, M.D., FACN.

Associate Professor

King Saud University

Participants will be randomly allocated into two study groups; intervention group (IG, n=15) and placebo group (PG, n=15). Computer-generated random numbers will be used to randomize the participants into one of two intervention groups.

The intervention-ONS and isocaloric-NOS will be served in opaque glasses of the same shape and color. the care providers (nurses, dietitians) will not know members of each groups or the nature or composition of the ONS.

The intervention group received a guidance regarding their diet and physical activity using the motivational interviewing strategy to improve adherence to healthy behaviors. Participants received a guide with a motivational interviewing approach, which served as the basis for the interview process. The objectives in the intervention group were to consume four vegetables and two fruits a day, seven days a week, increase fiber consumption to more than 30 g daily, reduce fat consumption to no more 20% of the total energy consumed, decrease the consumption of sugary drinks and increase protein intake. Another goal was to increase the number of steps to 4,000 additional steps to those who have already walked.

The comparison group received a guide on medical care and nutrition with a traditional educational approach. The indication was to read and learn about the health-related topics included in the booklet that was given to them. These participants were visited in the same way as the intervention group to answer questions and monitor participation throughout the intervention.

Body Weight Changes

Mammographic Density

Quality of Life

The motivational interviewing strengthens the motivation and commitment to achieve a specific change through the induction and exploration of the reasons for modifying behavior. All this within an atmosphere of acceptance and compassion. It is about extracting the possible solutions to the change that is faced from the individual and his environment and not from the professional. This strategy is achieved by looking for the patient to feel motivated, and to express their problem and thus create discrepancy so that they evaluate their actions and reflect on the changes they should make.

Motivational Interviewing

Traditional education refers to the normal care given to breast cancer survivors. That is, they receive recommendations about their physical activity and diet but without any motivational approach.

Traditional Education

Centro de Investigación en Alimentación y Desarrollo

Impact of Diet and Physical Activity Changes on Body Weight, Biomarkers and Quality of Life in Breast Cancer Survivors

Intervention Program to Promote Changes in Diet and Physical Activity and to Evaluate Its Impact on Body Weight, Biomarkers of Disease and Quality of Life in Breast Cancer Survivors

Change in the amount of dense tissue compared to the amount of fatty tissue in the breast on a mammogram reported in percentage

Change in score of the scale of the Quality of Life Patient/Cancer Survivor Version. questionnaire carried out by Ferrell et al., (2012). This questionnaire analyzes the dimensions of physical, emotional, social, and spiritual well-being through a Likert scale. The minimum score to be obtained is 42 and the maximum score is 210 points, where the higher the score, the better the quality of life and the lower the score, the worse the quality of life.

Change in score of the scale of the Pittsburgh Sleep Quality Index. This questionnaire uses a Likert-type scale and provides an overall score of the quality of sleep in a range of 0 to 21, where the highest score refers to greater difficulties in all areas of sleep and a lower score gives a better sleep quality

Absolute telomere length (kilobase pair) (kbp)

The amount of bone mineral in bone tissue in g/cm2

The Revised Vital Orientation Test (LOT-R) was used, which is made up of a total of 10 items with a Likert response with five response options (from 0 = "strongly disagree" to 4 = "strongly agree "). The higher the level of optimism, the higher the level of optimism.

The State-Trait Anxiety Inventory, STAI was used. This questionnaire has twenty items for each of the subscales that are state anxiety and trait anxiety, with an alternative Likert response scale (from 0 = "nothing" to 3 = "a lot" for state anxiety and for trait anxiety of 0 = "Almost never" to 3 = "almost always"). Totals range from 0 to 60 for each subscale, a higher score reflects higher levels of anxiety.

Actually there is no plan to share IPD to other researchers

Graciela Caire Juvera, PhD

Centro de Investigación en Alimentación y Desarrollo A.C.

National Council of Science and Technology, Mexico

The intervention group received the motivational interviewing and the comparison group an orientation with a traditional educational approach. Both groups were followed for 8 months and the changes in the variables of interest were analyzed.

Metabolic Syndrome

22 Patients will consume 600 mg Alpha lipoic acid for 12 weeks .

Alpha lipoic acid

Participants will be supplemented with 600 mg/day placebo (Starch).

Placebo

Alpha Lipoic Acid Supplementation and Metabolic Syndrome

Assessment of the Effect of Alpha Lipoic Acid Supplementation on Inflammatory Factors, Insulin Resistance, Glycemic Control and Anthropometric Indices in Patients With Metabolic Syndrome

Fasting blood glucose concentration (mg/dl)

Serum TG (triacylglycerol) concentration (mg/dl)

Serum TC (total cholesterol) concentration (mg/dl)

Dr. B.Abbasi

Clinical Professor

In this study, samples will be randomly divided into two groups receiving the supplement or placebo.

This study will be conducted as a parallel randomized double-blind clinical trial. patient will randomly be divided into two groups, each will receive supplement or placebo for 12 weeks .Before the study, containers will be coded as A and B by a person other than the study researchers according the concealment rules .

Group case: modified ketogenic diet to reduce at least 20% saturated fat, up> 50% of the acid supply monounsaturated, increasing> 50% polyunsaturated fatty acid content and a lower ratio w6 / w3 at least 50% compared to classic diet used by the control group

Epilepsy

Cardiovascular Disease

Non-alcoholic Fatty Liver Disease

ketogenic diet

Nagila Raquel Teixeira Damasceno

Impact of Ketogenic Diet on Lipoproteins in Refractory Epilepsy

Classic Ketogenic Diet and Modified: Evaluation of the Therapeutic Potential and Impact on the Oxidative Profile, Lipidomic, Inflammatory and Size of Lipoproteins in Children and Adolescents With Refractory Epilepsy

age, income, disease, parent´s education, use of drugs and supplements, type of seizures, questions about quality of life

phase angle mass by impedance bioeletrical

Food record applied during 3 days to each time

Concentration of B-hydroxybutirate in plasma. Determination with kit Ranbut (Randox Laboratories Limited, Reino Unido).

Concentration in plasma. Determination with kit NEFAS(Randox Laboratories Limited, Reino Unido)

beta carotene/akuutti patologinen solukuolema

Anti-inflammatory/Antioxidant Oral Nutrition Supplementation in COVID-19

Impact of Diet and Physical Activity Changes on Body Weight, Biomarkers and Quality of Life in Breast Cancer Survivors

Alpha Lipoic Acid Supplementation and Metabolic Syndrome

Impact of Ketogenic Diet on Lipoproteins in Refractory Epilepsy

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