broad bean/protease

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Point mutations in helper component protease of clover yellow vein virus are associated with the attenuation of RNA-silencing suppression activity and symptom expression in broad bean.

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Helper component protease (HC-Pro) is a potyvirus-encoded multifunctional protein and a major determinant of symptom expression in a susceptible plant. Here, we show the involvement of clover yellow vein virus (ClYVV) HC-Pro in necrotic symptom expression in broad bean (Vicia faba cv. Wase). In this

99mTc-labeled field bean protease inhibitor can function as an efficient tumor detecting agent.

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Purified field bean protease inhibitor (FBPI) was labeled with 99mTcO4- to ascertain its ability to locate tumors in tumor-bearing rat models. The labeling was done with Sn2+ as a reducing agent and the yield was 95%. It was stable for 2 hr at ambient temperature. The biodistribution study of the

Treatment with field bean protease inhibitor can effectively repress ethylnitrosourea (ENU)-induced neoplasms of the nervous system in Sprague-Dawley rats.

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The ability of field bean protease inhibitor (FBPI) to inhibit ethylnitrosourea (ENU)-induced tumours of the nervous system of Sprague-Dawley rats was investigated. Groups of 1-day-old rats were injected intraperitoneally (i.p.) with neurocarcinogenic amounts of ENU and a few hours later, one group

The field bean protease inhibitor has the potential to suppress B16F10 melanoma cell lung metastasis in mice.

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Metastasis is a characteristic and fatal feature of human malignancies. Its regulation is therefore of the utmost significance to clinicians. The present study was undertaken to determine whether a legume-derived protease inhibitor (PI) of trypsin/chymotrypsin, the field bean PI (FBPI), also has

Inhibition of benzopyrene-induced forestomach tumors by field bean protease inhibitor(s).

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Protease inhibitors (PIs), particularly the soybean-derived Bowman-Birk inhibitor, have proved to be powerful blockers of carcinogenesis in many in vitro and animal model systems. However, so far an ability of PIs to suppress gastric carcinogenesis has not been demonstrated, because of the

The field bean protease inhibitor can effectively suppress 7,12-dimethylbenz[a]anthracene-induced skin tumorigenesis in mice.

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Prolonged topical treatment with protease inhibitors (PIs) both synthetic and of bacterial origin have been shown to prevent carcinogen initiated and croton oil or phorbol acetate promoted skin carcinogenesis in mice. However, no one has yet examined the possibility of a purified PI of plant origin

Long-term feeding of field bean protein containing protease inhibitors suppresses virus-induced mammary tumors in mice.

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Protease inhibitors (PIs) of synthetic, bacterial or soybean origin have been shown to suppress carcinogen or radiation-induced rat mammary carcinogenesis. We report, for the first time, the effect of year-long feeding of Field bean meal, a rich source of PIs with a 24% protein content, at different

Field bean protease inhibitor preparations, unlike methotrexate, can completely suppress Yoshida sarcoma tumor in rats.

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Protease inhibitor preparations (PIP) with antitryptic and antichymotryptic activities, isolated from field bean legume as well as doxorubicin and cyclophosphamide could effectively suppress the growth of Yoshida sarcoma ascites tumor cells transplanted in adult rats and prevent their death. As

Purification and characterization of neutral protease from Aspergillus oryzae Y1 isolated from naturally fermented broad beans.

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The strain Y1, with a notably high production of neutral protease, was isolated from naturally fermented broad beans and subsequently identified as Aspergillus oryzae, through the analysis of its morphology characteristics and 18S rDNA sequence. Naturally fermented broad beans are the main raw

The effect of protease and Bacillus licheniformis on nutritional value of pea, faba bean, yellow lupin and narrow-leaved lupin in broiler chicken diets.

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This study investigated the nutritional value (digestibility of ileal crude protein and amino acids (AAs)) and the AME_N value of legumes (pea, faba bean, yellow lupin, and narrow-leaved lupin) with or without protease.Two hundred, one-day-old, male Ross 308 broiler chickens were randomly

A new peptidic protease inhibitor from Vicia faba seeds exhibits antifungal, HIV-1 reverse transcriptase inhibiting and mitogenic activities.

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A new trypsin-chymotrypsin Inhibitor, with an N-terminal sequence showing some differences from the previously reported trypsin-chymotrypsin inhibitor, was isolated from the broad bean Vicia faba. The inhibitor was a peptide with a molecular mass of 13 kDa. It was adsorbed on Affi-gel blue gel and

Field bean protease inhibitor mitigates the sister-chromatid exchanges induced by bromoform and depresses the spontaneous sister-chromatid exchange frequency of human lymphocytes in vitro.

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The mutagenicity of a trihalomethane-bromoform (CHBr3)-was assessed by the in vitro sister-chromatid exchange (SCE) assay using human peripheral blood lymphocytes. CHBr3 was found to induce SCEs significantly in a dose-dependent manner. When the cells were exposed to 600 ng CHBr3/ml of the medium,

Nutritional effects of field-bean (Vicia faba L.) protease inhibitors and field beans fed to rats [proceedings].

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Effect of extrusion pretreatment on the physical and chemical properties of broad bean and its relationship to koji preparation.

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The physicochemical properties of broad bean paste koji made from extruded and traditional steam-cooked raw materials were investigated by scanning electron micrographs (SEM), confocal laser scanning micrographs (CLSM), circular dichroism (CD) and Molecular weight (Mw) analysis. The results showed

Physiological aspects of fungi isolated from root nodules of faba bean (Vicia faba L.).

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The present study was made to isolate and assess some physiological characteristics of root nodule-colonizing fungi. During this study, 17 fungal species were isolated from root nodule samples taken from faba bean plants (Vicia faba L.) collected from different sites at Assiut area (Egypt). The

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