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cocaine/cannabis

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Sivu 1 alkaen 626 tuloksia

An epidemiologic investigation of marijuana- and cocaine-related palpitations.

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Laboratory studies and anecdotal reports by users suggest that palpitations often follow the administration of marijuana or cocaine. Epidemiologic strategies are used to detect this association using interview data from 6702 household residents sampled and followed prospectively for a collaborative
Reinforcing effects mediated by accumbal CB(1) receptors (CB(1)R) are controversial, as well as their role in the rewarding effects of cocaine. Accumbal glutamate and glutamate receptors have been proposed to be involved in CB(1)R-mediated effects on cocaine reward. Rewarding effects of cocaine can

Postdischarge cannabis use and its relationship to cocaine, alcohol, and heroin use: a prospective study.

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OBJECTIVE Research on the effects of cannabis on the brain and behavior has been surprisingly scarce. In humans, laboratory studies document toxicity and psychoactive effects of cannabinoids. However, among substance abuse patients, only a few studies have prospectively examined the relationship of

Marijuana and cocaine effect expectancies and drug use patterns.

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Self-reports from 704 college students were content analyzed and used to develop the Marijuana Effect Expectancy Questionnaire and Cocaine Effect Expectancy Questionnaire. Responses were examined using exploratory and confirmatory principle components analysis. Six marijuana expectancies (34.6% of

Psychedelic symptoms of cannabis and cocaine use as a function of trait impulsivity.

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Trait impulsivity has been linked to addiction in humans. It has been suggested that drug users with high trait impulsivity levels are more sensitive to subjective drug intoxication. This study assessed whether subjective response to drugs differs between drug users with normal or high levels of

Asthma associated with the use of cocaine, heroin, and marijuana: A review of the evidence.

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OBJECTIVE A review of the evidence was conducted regarding asthma associated with the use of cocaine, heroin, and marijuana. METHODS A search of the English literature was performed via PubMed/Medline and EMBASE using the search terms asthma AND cocaine, heroin, and marijuana. When pertinent

(AAT)n repeat in the cannabinoid receptor gene (CNR1): association with cocaine addiction in an African-Caribbean population.

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Owing to their agonist action on dopaminergic systems, cannabinoids may play a major role in substance dependency and schizophrenia. We examined the (AAT)n triplet repeat polymorphism nearby the CNR1 gene, which encodes human cannabinoid (CB1) receptor, in a male Afro-Caribbean population. The

From first drug use to drug dependence; developmental periods of risk for dependence upon marijuana, cocaine, and alcohol.

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The focal point of this paper is the transition from drug use to drug dependence. We present new evidence on risk for starting to use marijuana, cocaine, and alcohol, as well as risks for progression from first drug use to the onset of drug dependence, separately for each of these drugs. Data from

Protective effects of cannabinoid receptor agonists against cocaine and other convulsant-induced toxic behavioural symptoms.

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Based on the previously reported co-localization and relationship between cannabinoid and dopamine receptors, the effects of cannabinoid receptor agonists against cocaine-induced toxic behavioural symptoms, including convulsive seizures, were examined in mice. The anticonvulsant effect of several

The impact of cocaine and marijuana use on low birth weight and preterm birth: a multicenter study.

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OBJECTIVE Our aim was to evaluate prospectively the effects of cocaine and marijuana use on pregnancy outcomes. METHODS A prospective multicenter cohort study was conducted at seven university-based prenatal clinics in the United States from 1984 to 1989. The cohort described herein consisted of a

Neuroimaging in drug and substance abuse part I: cocaine, cannabis, and ecstasy.

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Multiple neurological complications of cocaine abuse have been described including both ischemic and hemorrhagic cerebrovascular events, atrophy in the case of chronic abuse, and an increase in incidence of congenital malformations in the setting of maternal use. The abuse of cannabis may cause a

Elevated plasma norepinephrine after in utero exposure to cocaine and marijuana.

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OBJECTIVE To compare plasma catecholamine concentrations between cocaine-exposed and unexposed term newborns and to determine the relationship between plasma catecholamines and newborn behavior. METHODS Forty-six newborn infants participating in a prospective study of the neonatal and long-term

Cannabis, cocaine, and visuomotor integration: evidence for a role of dopamine D1 receptors in binding perception and action.

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The primate cortex represents and produces events in a distributed way, which calls for a mechanism that integrates their features into coherent structures. Visuomotor integration seems to be driven by dopaminergic (DA) pathways but which subsystems are involved is currently unknown. The present

A decrement in probabilistic category learning in cocaine users after controlling for marijuana and alcohol use.

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Aspects of stimulus-response (S-R) learning, mediated by striatal dopamine signaling, have been found to be altered in cocaine users relative to healthy controls. However, the influence of cocaine users' marijuana and alcohol use has not been accounted for. This study evaluated S-R learning and

Persistent anxiogenic effects of a single or repeated doses of cocaine and methamphetamine: interactions with endogenous cannabinoid receptor ligands.

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As persistent behavioural changes, such as increased anxiety-related behaviours, can be predicted based on the phenomenon of psychostimulant-induced neuronal plasticity, the time course (3-, 5- and 10-day time points) of the effects of both a single and repeated (daily for 7 days) i.p.
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