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Sivu 1 alkaen 27 tuloksia
Coumarin derivatives for cancer therapy
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BACKGROUND
Pancreatic cancer is one of the most devastating human cancers and is the fourth leading cause of overall cancer-related mortality in the United States. Currently, there is no clinically effective therapy for pancreatic cancer. The only chance for complete recovery is surgical resection;
Coumarin derivatives for cancer therapy
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BACKGROUND
Pancreatic cancer is one of the most devastating human cancers and is the fourth leading cause of overall cancer-related mortality in the United States. Currently, there is no clinically effective therapy for pancreatic cancer. The only chance for complete recovery is surgical resection;
Coumarin compounds and their use for treating cancer
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BACKGROUND
Cancer is a leading cause of death in developed countries. Despite continuing advances in diagnosis and treatment regimens, most existing treatment methods have undesirable side effects and limited efficacy. Treatment of cancer is complicated by the variety of mechanisms involved in the
Coumarin derivatives and methods of use in treating hyperproliferative diseases
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BACKGROUND
A variety of diseases involve the hyperproliferation of cells. Cancer, for example, is a commonly known hyperproliferative disease. Cancer is a large, heterogeneous class of diseases in which a group of cells display uncontrolled growth, resulting in an invasion that intrudes upon and
Coumarin-amide derivatives and its preparation, said drug composition and its use
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TECHNICAL FIELD
The present invention relates to novel coumarins, their carboxamide derivatives, the preparation method thereof and the pharmaceutical compositions containing them, and their use as medicaments for kidney protection, as well as for the treatment of hypertension,
Condensation product of theanine derivative and carboxylic acid coumarin derivative, its intermediate, preparation method and use thereof
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CROSS-REFERENCE
This application claims priority under 35 U.S.C. .sctn.371 to Patent Cooperation Treaty application PCT/CN2013/084146, filed Sep. 25, 2013, which claims the benefit of Chinese patent application no. 201210363366.6, filed Sep. 27, 2012; Chinese patent application no. 201210363367.0,
Coumarin derivative and use thereof
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This application is a 371 of PCT/JP94/00615 filed 12 Apr. 1994 and published as WO94/24119 Oct. 27, 1994.
TECHNICAL FIELD
The present invention relates to novel coumarin derivatives inhibiting 12-lipoxygenase selectively, and medicines containing these compounds as effective ingredients; and
Coumarin-chalcones as anticancer agents
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CROSS-REFERENCE TO RELATED APPLICATIONS
The present application is a National Phase of and claims the benefit of PCT/IN2011/000515, with an international filing date of Aug. 5, 2011, which in turn claims priority to Indian Application No. 1843/DEL/2010, filed Aug. 5, 2010, the entire disclosures of
4-substituted coumarin derivatives and preparation methods and uses thereof
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CROSS-REFERENCE TO RELATED APPLICATIONS
This application is a U.S. National Phase Application of PCT/CN2016/074796, filed Feb. 29, 2016, which claims priority to CN 201510618234.7, filed Sep. 24, 2015, the contents of which applications are incorporated herein by reference in their entirety for all
Chalcone coumarins
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FIELD OF THE INVENTION
The invention relates to a novel class of compounds which have a structures related to naturally and synthetically occurring chalcones, as well as to methods for preparation of such compounds and to pharmaceutical uses thereof.
TECHNICAL FIELD
The compound
Coumarin derivative
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FIELD OF INVENTION
The present invention relates to medicaments for enhancing the effect of cancer therapy on the basis of mechanism of injuring DNA, and novel compounds useful as active ingredients of said medicament.
BACKGROUND ART
Anticancer agents are administered in treatments of cancer
Derivatives of flavones, xanthones and coumarins
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FIELD OF THE INVENTION
The invention relates to a class of compounds which have a structure related to naturally and synthetically occurring flavanoids and to pharmaceutical uses of the compounds.
TECHNICAL FIELD
The development of multiple drug resistance represents an increasing problem in cancer
Coumarin based Hsp90 inhibitors with urea and ether substituents
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BACKGROUND OF THE INVENTION
I. Field of the Invention
The present invention relates generally to the fields of biology, chemistry, and medicine. More particularly, it concerns compounds, compositions and methods for the treatment and prevention of diseases such as cancer and other proliferative
Triazole modified coumarin and biphenyl amide-based HSP90 inhibitors
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BACKGROUND OF THE INVENTION
I. Field of the Invention
The present invention relates generally to the fields of biology, chemistry, and medicine. More particularly, it concerns compounds, compositions and methods for the treatment and prevention of diseases such as cancer and other proliferative
Method for imaging cell using fluorescence-labeled sugar derivative having coumarin derivative bound thereto, and imaging agent
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TECHNICAL FIELD
The present invention relates to a novel fluorescently labeled sugar derivative to which a specific coumarin derivative has been linked, and to a cell imaging method and an imaging agent using the same. Further, the present invention relates to a method for detecting and/or imaging
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