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The 1988 Consensus Conference on the Methodology of Clinical Trials of Antidepressants developed a European viewpoint on the methodology of measuring the efficacy of antidepressants. Placebo-controlled, parallel group trials are necessary but problematic. To test the efficacy of a new
DEPRESS (Depression Research in European Society) is the first large pan-European survey of depression in the community. A total of 13359 of the 78463 adults who participated in screening interviews across six countries were identified as suffering from depression, a 6-month prevalence of 17%. Major
BACKGROUND: Evaluating treatments for depression is of great importance given that estimates of lifetime prevalence range up to 20 per cent. The class of antidepressants known as Selective Serotonin Reuptake Inhibitors (SSRIs) has been a major innovation in this area, but has also raised questions
Despite the numerous warnings of European and national drug agencies as well as clinical guidelines since the year 2004, psychotropic drugs are still frequently used in dementia. A systematic review comparing the use of psychotropic drugs in nursing homes from different European countries is
BACKGROUND
Prescribing of antidepressants varies widely between European countries despite no evidence of difference in the prevalence of affective disorders.
OBJECTIVE
To investigate associations between the use of antidepressants, country-level spending on healthcare and country-level attitudes
A survey was conducted among European neurologists to obtain information on their interest in, knowledge on, and practice in the treatment of neuropathic pain. A simple questionnaire with 11 closed and one open question was distributed at national meetings, via e-mail lists of national Neurological
The Research Network of the European Association for Palliative Care (EAPC) performed a survey of 3030 cancer patients from 143 palliative care centres in 21 European countries. The survey addressed pain intensity and the use of non-opioid analgesics, adjuvant analgesics and opioids. Patients were
The consumption in France of psychotropic drugs, of all classes, except for neuroleptics, is great, even very great, and largely superior to that observed in neighbouring European countries such as Germany, Spain, Italy and the United Kingdom. With regard to hypnotics and anxiolytics, 5 to 7 per
BACKGROUND
The majority of Huntington's disease (HD) mutation carriers experience some psychopathology during their lifetime, varying from irritability to psychosis, but prevalences of particular symptoms vary widely due to diverse study populations in different stages of HD and the use of different
This European guideline for the diagnosis and treatment of insomnia was developed by a task force of the European Sleep Research Society, with the aim of providing clinical recommendations for the management of adult patients with insomnia. The guideline is based on a systematic review of relevant
People with severe mental illnesses, such as schizophrenia, depression or bipolar disorder, have worse physical health and reduced life expectancy compared to the general population. The excess cardiovascular mortality associated with schizophrenia and bipolar disorder is attributed in part to an
OBJECTIVE
To analyse the consumption of a number of medicines with a known potential for increasing the risk of road traffic accidents in the general population of Europe.
METHODS
Questionnaires were distributed through the European Drug Utilization Research Group (EuroDURG) and Post-Innovation