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Sivu 1 alkaen 93 tuloksia
Method for diagnosing hepatic fibrosis
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The present invention concerns methods for diagnosing liver fibrosis in a subject suffering from obesity, or for selecting a subject suffering from obesity for liver biopsy or for treatment. The present invention also pertains to methods for screening a probiotic, a prebiotic, a chemical compound or
Method for treating obesity
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FIELD OF INVENTION
The present invention relates to a method for lowering blood glucose and method for treating and/or preventing disease including hepatic disease, obesity and diabetes.
BACKGROUND OF INVENTION
Recently, the altering life style in the modern society results in the switch of dietary
Organic compounds
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This application is the National Stage of Application No. PCT/US07/64974 filed Mar. 27, 2007, which claims benefit under 35 U.S.C. .sctn.119(e) of U.S. Provisional Application No. 60/787,104, filed Mar. 29, 2006, the contents of which are incorporated herein by reference in their entirety.
The
Quaternary ammonium compounds
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DESCRIPTION OF RELATED APPLICATIONS
This application claims priority under 35 U.S.C. .sctn. 119 to Japanese Patent Application No. 2002-248586 filed on Aug. 28, 2002, Japanese Patent Application No. 2002-364725 filed on Dec. 17, 2002, U.S. Provisional Application Ser. No. 60/407291 filed Sep. 3,
Organic compounds
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The present invention relates to novel imidazole derivatives that are used as aldosterone synthase inhibitors, as well as for treatment of a disorder or disease mediated by aldosterone synthase (CYP11B2) and/or 11-beta-hydroxylase (CYP11B1).
The present invention provides a compound of formula
Organic compounds
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The present invention relates to novel imidazole derivatives that are used as aldosterone synthase and aromatase inhibitors, as well as for treatment of a disorder or disease mediated by aldosterone synthase or aromatase.
The present invention provides a compound of formula (I)
##STR00002## wherein
Organic compounds
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The present invention relates to novel imidazole derivatives that are used as aldosterone synthase and aromatase inhibitors, as well as for treatment of a disorder or disease mediated by aldosterone synthase or aromatase.
The present invention provides a compound of formula (I)
##STR00002## wherein
Organic compounds
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The present invention relates to novel imidazole derivatives that are used as aldosterone synthase and aromatase inhibitors, as well as for treatment of a disorder or disease mediated by aldosterone synthase or aromatase.
The present invention provides a compound of formula (I)
##STR00002## wherein
Acylhydrazone derivatives and the use thereof in the inhibition, regulation and/or modulation of kinase signal transduction
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BACKGROUND OF THE INVENTION
The invention had the object of finding novel compounds having valuable properties, in particular those which can be used for the preparation of medicaments.
The present invention relates to compounds in which the inhibition, regulation and/or modulation of kinase signal
Heteroatom-linked substituted piperidines and derivatives thereof useful as histamine H.sub.3 antagonists
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FIELD OF THE INVENTION
The present invention relates to heteroatom-linked substituted piperidines and derivatives thereof useful as histamine H.sub.3 antagonists. The invention also relates to pharmaceutical compositions comprising said compounds and their use in treating inflammatory diseases,
Heteroatom-linked substituted piperidines and derivatives thereof useful as histamine H.sub.3 antagonists
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FIELD OF THE INVENTION
The present invention relates to heteroatom-linked substituted piperidines and derivatives thereof useful as histamine H.sub.3 antagonists. The invention also relates to pharmaceutical compositions comprising said compounds and their use in treating inflammatory diseases,
Carbon-linked substituted piperidines and derivatives thereof useful as histamine H.sub.3 antagonists
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FIELD OF THE INVENTION
The present invention relates to carbon-linked substituted piperidines and derivatives thereof useful as histamine H.sub.3 antagonists. The invention also relates to pharmaceutical compositions comprising said compounds and their use in treating inflammatory diseases, allergic
Fibronectin based scaffold domain proteins that bind to myostatin
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FIELD OF THE INVENTION
The present invention relates to fibronectin-based scaffold domain proteins that bind myostatin. The invention also relates to the use of the innovative proteins in therapeutic applications to treat muscle-wasting diseases and metabolic disorders. The invention further relates
Fibronectin based scaffold domain proteins that bind to myostatin
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FIELD OF THE INVENTION
The present invention relates to fibronectin-based scaffold domain proteins that bind myostatin. The invention also relates to the use of the innovative proteins in therapeutic applications to treat muscle-wasting diseases and metabolic disorders. The invention further relates
Fibronectin based scaffold domain proteins that bind to myostatin
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FIELD OF THE INVENTION
The present invention relates to fibronectin-based scaffold domain proteins that bind myostatin. The invention also relates to the use of the innovative proteins in therapeutic applications to treat muscle-wasting diseases and metabolic disorders. The invention further relates
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