Patient with mass effective brain tumor that undergo non-invasive intracranial pressure measurement

Tumor, Brain

Intracranial Pressure Increase

Non-invasive measurement of intracranial pressure in patients with mass effective brain Tumors

Non-invasive measurement of intracranial pressure

Kantonsspital Aarau

non_invasive_aICP_Tumor

Non-Invasive Measurement of Absolute Intracranial Pressure in Patients With Mass Effective Brain Tumors

The primary outcome is the non-invasive, absolute intracranial pressure (aICP) before brain tumor surgery, as determined by the "NON-INVASIVE ICP ABSOLUTE VALUE METER" in mmHG.

The secondary outcome is to demonstrate correlation between increased aICP and clinical and radiological signs.

Javier Fandino, MD

Neoplasms

Nervous System Disease

Vestibular Disease

National Institutes of Health Clinical Center, 9000 Rockville Pike

Using Positron Emission Tomography to Predict Intracranial Tumor Growth in Neurofibromatosis Type II Patients

Using Positron Emission Tomography (PET) to Predict Intracranial Tumor Growth in Neurofibromatosis Type II (NF2) Patients

National Institute of Neurological Disorders and Stroke (NINDS)

All patients will undergo the following standard imaging and radiotherapy procedures will be performed for each patient:
Standard MRI for radiotherapy treatment planning which takes about 60 minutes.
Radiotherapy treatment simulation with CT.
Radiotherapy treatment planning
Radiotherapy treatment
Routine follow-up every 3 months after the radiotherapy.
Special Procedures.
The following special imaging and radiotherapy procedures will be performed for each patient:
fMRI (30 minutes)
The 3MS examination, administered every 3 months during routine follow-up for one year after the completion of the radiotherapy.

Brain Tumors

Functional magnetic resonance imaging (fMRI) uses MR imaging to measure the tiny metabolic changes that take place in an active part of the brain. fMRIs are used for many reasons, for example, to determine precisely which part of the brain is handling critical functions such as thought, speech, movement and sensation, to help assess the effects of stroke, trauma or degenerative disease (such as Alzheimer's) on brain function, and to guide the planning of surgery and radiation therapy.

fMRI Evaluation

Weill Cornell Medical College

Dose Response of Functionally Critical Brain Regions for Brain Radiotherapy

Phase I Study of Dose Response of Functionally Critical Brain Regions for Brain Radiotherapy

fMRI screening at baseline and 6 months after the completion of radiation therapy to observe the original functionality of the brain (pre-radiation therapy) and the functionality of the brain after radiation therapy. If the radiation has damaged any functional areas, the difference in performance will be evident in the 6 month fMRI.

The expanded MMSE (mini-mental status exam) routinely used to screen the overall cognitive functions of patients following brain radiotherapy. The MMSE will help to track brain function at a great interval than the fMRI. It will show changes in the brain over time.

meningioma/seizures

non_invasive_aICP_Tumor

Using Positron Emission Tomography to Predict Intracranial Tumor Growth in Neurofibromatosis Type II Patients

Dose Response of Functionally Critical Brain Regions for Brain Radiotherapy

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