Infants randomized into the "CC+SI group" will receive a SI with a PIP of 25-30 cmH2O while receiving chest compression. The SI will be delivered over a period of 45 seconds. This will be followed by PEEP of 5-8 cm water to perform an assessment of the newborn's heart rate. If heart rate is >60/min continue with standard care as per local hospital policy (standard hospital practice guideline). If heart rate remains <60/min continue with CC+SI for another 45sec at which time a further assessment should be performed. If heart rate remains <60/min continue with CC+SI.

Infants randomized into the "3:1 C:V group" will receive CC at a rate of 90/min and 30 ventilations/min in a 3:1 C:V ratio as recommended by the current resuscitation guidelines.

Heart Arrest

Birth Asphyxia

Bradycardia

chest compression will be delivered during sustained inflation (CC+SI). The duration of each sustain inflation is 20sec. After 20sec a pause of 1sec id done before the next sustained inflation is delivered for another 20sec. Chest compressions are given continuously. This approach is continued until return of spontaneous circulation.

CC+SI

During 3:1 C:V. 3 chest compressions are given, then stopped and then 1 inflation is given. This approach is continued until return of spontaneous circulation.

3:1 C:V

Provides public information about the study and has a secure area for investigators

Royal Womens Hospital

King Edward Memorial Hospital for Women

Medical University Graz

Medical University Vienna

Royal Alexandra Hospital

IWK Health Centre

McMaster Children's Hospital

CHU Sainte-Justine

Hong Kong University

University College Cork

Ospedale dei Bambini Vittore Buzzi

Akershus University Hospital

Poznan University of Medical Sciences

Division of Neonatology Department of Pediatrics, Sidra Medicine

SI + CC Versus 3:1 C:V Ratio During Neonatal CPR

SURV1VE-Trial - Sustained Inflation and Chest Compression Versus 3:1 Chest Compression to Ventilation Ratio During Cardiopulmonary Resuscitation of Asphyxiated Newborns: A Randomized Controlled Trial

Duration of chest compression heart rate is >60/min for 60sec.

Number of infants who die until discharge - comparison between group

How many doses of epinephrine are given - comparison between group

Brain injury either by ultrasound or magnet resonance imaging - comparison between group

Number of infants who develop Necrotizing enterocolitis - comparison between group

University of Alberta

Convulsive Status EPILEPTICUS

procedure of moderate hypothermia therapy, between 32 ° and 34 ° C for 24 hours

Moderate hypothermia

Hôpital André MIGNOT- Service de réanimation médico-chirurgical

Evaluation of Therapeutic Hypothermia in Convulsive Status EPILEPTICUS in Adults in Intensive Care

Evaluation of the Interests of a Therapeutic Hypothermia Procedure in Convulsive Status EPILEPTICUS in Adults in Intensive Care - HYBERNATUS Study

Functional impairment is defined by a Glasgow Outcome Scale strictly less than 5.
The time of evaluation should be 3 months (+/- 1 week)

Judged on the frequency of seizures, the recurrence of epileptic status after hospitalization, the number of anti-epileptic drug, mini mental score (MMS).

Judged on the frequency of seizures within 24 hours after status epilepticus onset (refractory status epilepticus on day 1) and on the frequency of seizures within 48 hours after anesthetic treatment withdrawal (super refractory status epilepticus)

ventricular fibrillation/seizures

SI + CC Versus 3:1 C:V Ratio During Neonatal CPR

Evaluation of Therapeutic Hypothermia in Convulsive Status EPILEPTICUS in Adults in Intensive Care

PIoglitazone for PrEvention of Restenosis in Diabetic Patients

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