xerostomia/cannabis

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Cannabinoids and metabolites in expectorated oral fluid following controlled smoked cannabis.

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BACKGROUND ∆(9)-Tetrahydrocannabinol (THC) in oral fluid (OF) implies cannabis intake, but eliminating passive exposure and improving interpretation of test results requires additional research. METHODS Ten adult cannabis users smoked ad libitum one 6.8% THC cigarette. Expectorated OF was collected

Cannabis and caries--does regular cannabis use increase the risk of caries in cigarette smokers?

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The use of cannabis by adolescents in Switzerland has almost doubled in the past decade. Empirical observations in private dental practices indicate that cannabis users have more carious lesions than those who do not use cannabis. The aim of this study was to investigate the hypothesis that regular

New approaches in the management of spasticity in multiple sclerosis patients: role of cannabinoids.

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Cannabinoids such as Cannabis-based medicinal extracts (CBMEs) are increasingly being used in the treatment of spasticity associated with multiple sclerosis (MS). They have been shown to have a beneficial effect on spasticity; however, this evidence is largely based on subjective rating scales.

Medical marijuana use in head and neck squamous cell carcinoma patients treated with radiotherapy.

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The purpose of the study was to better understand why patients with history of head and neck cancer (HNC) treated with radiotherapy are using medical marijuana (MM). Established HNC quality of life questionnaires and our own MM quality of life questionnaire were sent to 15 HNC patients treated at

Occupational Exposure to Secondhand Cannabis Smoke Among Law Enforcement Officers Providing Security at Outdoor Concert Events.

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Numerous states within the USA have legalized cannabis for medical or non-medical (adult/recreational) use. With the increased availability and use of cannabis, occupational and environmental exposures to secondhand cannabis smoke (SHCS) raise concerns over whether non-users may be at

The synthetic cannabinoid JWH-018 modulates Saccharomyces cerevisiae energetic metabolism.

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Synthetic cannabinoids are a group of novel psychoactive substances with similar properties to Δ9-THC. Among the vast number of synthetic cannabinoids, designed to be tested in clinical trials, JWH-018 was the first novel psychoactive substance found in the recreational drug marketplace. The

The safety of cannabinoids for the treatment of multiple sclerosis.

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The evidence for the therapeutic efficacy of cannabinoids in the treatment of multiple sclerosis (MS) is increasing but is not as yet convincing. Although several trials have reported no significant effect, the majority of the evidence which supports a beneficial effect on spasticity and pain is

Cannabis and Radiation Therapy: A Scoping Review of Human Clinical Trials.

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It is estimated that at least 20% of Canadian patients with cancer use cannabis to alleviate symptoms of their disease and/or cope with the side effects of their treatment. Most patients want to learn more about cannabis from their healthcare team, but most oncology professionals feel

Candidiasis of the tongue in cannabis users: a report of 2 cases

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Cannabis, a psychoactive drug widely used for medicinal, recreational, and religious purposes, can have detrimental effects on several body systems, including the respiratory, cardiovascular, and central nervous systems. The use of cannabis in cigarette form can produce a series of oral alterations,

[The effects of cannabis and THC].

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Cannabis and THC exert manifold actions on a number of organ systems. A lethal dose of THC in humans is unknown. Above the psychotropic threshold, ingestion of cannabis causes an enhanced well-being and relaxation with an intensification of ordinary sensory experiences. The most important unwanted

Cannabis use and oral diseases.

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METHODS Medline and the Cochrane Central register of controlled trails (CENTRAL). METHODS Randomised Controlled Trials, Controlled Clinical Trials and Cohort Studies conducted on humans investigating cannabis usage were included. Screening was performed independently by two reviewers. Only English

Are cannabinoids a new treatment option for pain in patients with fibromyalgia?

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Preliminary studies suggest that the synthetic cannabinoid nabilone might be an effective therapy in patients with fibromyalgia. Skrabek et al. performed a double-blind, randomized, placebo-controlled clinical trial to analyze the effects of nabilone on pain and quality of life in patients with

Self-Reported Effectiveness and Safety of Trokie® Lozenges: A Standardized Formulation for the Buccal Delivery of Cannabis Extracts.

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Therapeutic use of cannabinoids, the main active ingredients of Cannabissativa L., is often hindered by their limited bioavailability and undesirable psychoactivity. We conducted an observational study in December 2016 and another one in February 2018 to investigate respectively: (i) the

Change in effects from marijuana: a five- to six-year follow-up.

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A five- to six-year follow-up study of 97 regular marijuana users in a large Midwestern city showed that the effect of marijuana intoxication remained fairly stable over time. However, continued use of the drug was associated with a decrease in pleasurable effects. Undesirable effects persisted but

The efficacy and safety of nabilone (a synthetic cannabinoid) in the treatment of anxiety.

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The anxiolytic properties of nabilone, a synthetic cannabinoid resembling the natural cannabinoids, were studied in 25 outpatients suffering from anxiety. The drug was compared with a placebo in a double-blind manner over a 28-day treatment period. Patients were seen weekly by the physician and were

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