Metabolic imbalance and vitamin D deficiency in type 1 diabetes in the Algerian population.

We aimed to assess Vitamin D levels in patients with Type 1 Diabetes (T1D) and investigate the correlation between the vitamin D and metabolic imbalance. Materiel and Methods: For our study we selected thirty-one patients with T1D without complications and fifty seven healthy controls. Diabetic patients were diagnosed using the criteria of the World Health Organization/American Diabetes Association. The Vitamin D, Parathyroid Hormone (PTH), insulin and C peptide assay were performed using chimilunescence. Glucose level, lipid profil, glycated hemoglobin (HbA1C) and ionogram were also performed.Vitamin D, HbA1c and Gly levels were found to be significantly in T1D patients than in controls (P<0.5). However, for PTH no significant difference were shown (P > 0. 05) and the results show a non significant difference of cholesterol total potassium, sodium, phosphor and calcium concentration averages.Our results indicate that deficiency of VD is associated with increased risk of T1DM in Algerian population.