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anisodamine/hémorragie
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[The effect of anisodamine on lipoprotein metabolism in the liver and the plasma membrane phospholipids of the hepatocytes in hemorrhagic shock].
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The effect of anisodamine on lipoprotein metabolism in the liver and hepatocyte membrane phospholipids was studied on a model of hemorrhagic shock. Preliminary injection of anisodamine raised the content of very low-density lipoproteins in blood of the central vessels and intensified the breakdown
[Effect and significance of anisodamine on IkappaB kinase-beta in Kupffer cells following hemorrhagic shock].
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OBJECTIVE
To investigate the possible role of IkappaB kinase-beta (IKK-beta), the pathogenesis of hepatic injury induced by resuscitation of hemorrhagic shock and endotoxin, and to evaluate the preventive effect of anisodamine (654-2).
METHODS
Twenty-seven rabbits were randomly divided into the
Beneficial effect of anisodamine in hemorrhagic shock.
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Anisodamine , an alkaloid extracted from Anisodus tanguticus , is widely used in China in the treatment of septic shock, but its mechanism of action is unknown. We studied its antishock action in cats in a well controlled model of hemorrhagic shock. A bolus dose of 1 mg/kg was given intravenously 20
[Protective effects of Salviae miltiorrhizae and anisodamine (654-2) against early lung injury in acute hemorrhagic necrotizing pancreatitis in the dog].
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Experimental study had been conducted on 18 healthy adult mongral dogs of both sex, weighting from 7.5-11 kg, randomly divided into four groups. Experimental models of acute hemorrhagic necrotizing pancreatitis (AHNP) were established by retrograde injecting 1 ml/kg of sodium taurocholate directly
Enteric administration of anisodamine in the treatment of hemorrhagic shock.
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[Comparison between the protective effects of anisodamine and dexamethasone on visceral lysosomes of cats in hemorrhagic shock].
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A comparison of the effectiveness of anisodamine and noradrenaline on hemorrhagic shock in rabbits.
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Obscure gastrointestinal bleeding: diagnostic performance of 64-section multiphase CT enterography and CT angiography compared with capsule endoscopy.
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OBJECTIVE
To compare the diagnostic capabilities between capsule endoscopy (CE) and multislice CT (MSCT) enterography in combination with MSCT angiography for assessment of obscure gastrointestinal bleeding (OGIB).
METHODS
A total of 127 patients with OGIB were looked at in this study. 82 patients
Mechanism of the therapeutic effect of anisodamine in disseminated intravascular coagulation: study of platelet adhesion and aggregation, malondialdehyde, thromboxane B2, 6-keto-prostaglandin F1 alpha, and microcirculation.
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Acute disseminated intravascular coagulation (DIC) is a life-threatening condition that may be encountered in many situations, especially in cases of shock with uncontrollable hemorrhage. Anisodamine, an alkaloid extracted from a Chinese herb, is well known for its dramatic therapeutic effect on
[Effects of anisodamine on blood coagulation, fibrin and thrombosis in rabbits].
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Anisodamine at dose of iv 10 and 20 mg/kg prolonged plasma prothrombin time, bleeding time and coagulation time, and showed positive reaction of plasma protamine paracoagulation test in conscious rabbits. The drug prolonged the thrombin time and reduced the contend of plasma fibrin. Anisodamine
Cell protection mechanism of antishock action of anisodamine.
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Anisodamine was used as an antishock (chiefly septic) drug beginning in the early 1960s in China. Its underlining mechanism was believed to be due to its vasodilative action. But in normal animals it only produces slight vasodilation. Our work during the recent 15 years proved that anisodamine is
Effects of anisodamine on the expressions of vascular endothelial growth factor and intercellular adhesion molecule 1 in experimental infusion phlebitis.
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BACKGROUND
Infusion phlebitis is the most common side effect of clinical intravenous drug therapy and several clinical studies have demonstrated that anisodamine can effectively prevent the occurrence of infusion phlebitis. This study was designed to investigate effects of anisodamine on the
Comparison of myocardial microcirculatory perfusion after catheter-administered intracoronary thrombolysis with anisodamine versus standard thrombus aspiration in patients with ST-elevation myocardial infarction.
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Experimental study in rabbits of the antishock effect of anisodamine (654-2), and its mechanism of action.
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The antishock effect of anisodamine (654-2) was observed in different kinds of experimental shock in groups of rabbits--due to late hemorrhage, superior mesenteric artery occlusion, and septic shock from peritonitis. The drug 654-2 significantly alleviated the progress of shock and increased the
Salutary effects of anisodamine in murine traumatic shock.
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Anisodamine, an alkaloid originally extracted from the Chinese herb Anisodus tanguticus, has been reported to possess beneficial actions in septic, superior mesenteric artery occlusion, and hemorrhagic shock. We have investigated its actions in traumatic shock in rats. Anisodamine (2.5 mg/kg)
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