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anticonvulsant/accident vasculaire cérébral

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Methylenetetrahydrofolate Reductase Deficiency in Ischemic Stroke

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Epileptic seizures that begin in adulthood seriously affect patients, their relatives and the society in which they live financially and psychologically. The etiology of epileptic seizures starting at adult age includes head trauma, central nervous system infections, intracranial lesions,

Nucleotide Protein -3 in Epileptic Children

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Epilepsy affects approximately 1% of the world population. Lifetime prevalence of childhood and adolescence epilepsy (children <18 years) in Upper Egypt was 9.7/1000, with higher prevalence among children <12 years (10.8/1000). There is a clear cause for epilepsy in only a minority of the cases,

The Role of Concomitant Diseases in Postoperative Complications Risk Stratification.

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Advances in modern anesthesiology have significantly reduced the risk of anesthesia compared to the last century, however, the level of perioperative hospital mortality of planned operations at the moment is on average about 0.5% (ISOS group, 2016). Weiser et al. (2016) estimated that more than 313

Maraviroc to Augment Rehabilitation Outcomes After Stroke

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Background After stroke, the combination of progressive skills practice in an adequate dose, exercise for fitness, and reduced sedentary time will augment motor and cognitive outcomes. Sensorimotor and cognitive improvements after stroke often reach a general plateau by approximately 12 weeks after

Translational Study of the Effects of Neural Mobilization in Patients With Lomboisquiatalgia

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Translational study of the effects of Neural Mobilization in patients with lomboisquiatalgia The spinal nerve injury in humans often results in neuropathic pain characterized by spontaneous burning pain accompanied by allodynia and hyperalgesia [1]. These signs and symptoms occur in the continuous

Effect of Periodontitis on Bone Mineral Density in Postmenopausal Women

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Rapid estrogen level decline after menopause is associated with systemic bone loss in women leading to osteopenia/osteoporosis. Estrogen therapy (ET) improves bone mineral density (BMD) in postmenopausal women. Currently, ET has been associated with statistically significant increased risk of breast

The Use of Medicinal Cannabinoids as Adjunctive Treatment for Medically Refractory Epilepsy

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This is an observational study of a family's choice to use MCBD and the effect of this substance on medically refractory epilepsy in children. The risks associated with this use are not well known. There have recently been reports of stroke, liver dysfunction and altered anticonvulsant levels. In

Maternal and Neurodevelopmental Outcomes of in Utero Antiepileptic Drug (AED) Exposure

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There is a compelling need for prospective, properly controlled studies in women with epilepsy (WWE) during pregnancy to improve maternal and child outcomes. The proposed investigations are pertinent to the National Institute of Neurological Disorders and Stroke Epilepsy Research Benchmarks and will

Preventing Brain Injury in Infants With Congenital Heart Disease

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Infants with cyanotic congenital heart disease undergoing surgery in the neonatal period have a high rate of brain injury resulting in seizures, stroke, cerebral palsy, and neurodevelopmental delays. Neuroimaging abnormalities are found in 30% to 60% of cases and neurodevelopmental impairments occur

Evaluation of Therapeutic Hypothermia in Convulsive Status EPILEPTICUS in Adults in Intensive Care

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Status EPILEPTICUS (SE) is a major medical emergency. The incidence per 100,000 population has been estimated at 9.9 episodes in Europe and 41 episodes in the US. The overall morbidity and mortality associated with convulsive SE (CSE) is 60% at three months. The alteration of functional prognosis of

Safety and Efficacy of Topiramate in Neonates With Hypoxic Ischemic Encephalopathy Treated With Hypothermia

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Neonatal hypoxic-ischemic encephalopathy, due to perinatal asphyxia, is one of the leading causes of cerebral palsy, whose incidence, despite improvements in perinatal practice and neonatal care, has remained essentially unchanged over the recent past decades. It occurs approximately in 2-3 newborns

Levetiracetam Versus Carbamazepine in Post-Stroke Late Onset Crisis

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Stroke is the most common cause of seizures in the elderly and seizures are among the most common sequelae of stroke. About 10% of patients experience seizures since stroke onset up to several years (Silverman 2002). Arbitrarly a cut point of 2 weeks divide early seizures from late seizures (Honey

rEEG Guided Pharmacotherapy of Subjects With Depression Treatment Failure

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This study is testing a process (rEEG)for selecting the most appropriate medication(s) to treat a patient's depression versus a control group being treated according to a standardized method, the modified Star*D Algorithm. Qualified subjects will be randomized to the experimental (rEEG guided)

Anticonvulsant Mood Stabilizers, Antipsychotic Drugs and the Insulin Resistance Syndrome

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Homocysteine Study (HOST)

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Primary Hypothesis: The primary objective of this proposal is to test the hypothesis that administration of folate, pyridoxine (vitamin B6) and cyanocobalamin (vitamin B12) in high doses to patients with advanced chronic renal failure or end-stage renal disease and abnormally high plasma
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