aristolochia griffithii/hémorragie

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Snakebites and ethnobotany in the northwest region of Colombia. Part III: neutralization of the haemorrhagic effect of Bothrops atrox venom.

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Thirty-one of 75 extracts of plants used by traditional healers for snakebites, had moderate or high neutralizing ability against the haemorrhagic effect of Bothrops atrox venom from Antioquia and Chocó, north-western Colombia. After preincubation of several doses of every extract (7.8-4000

The toxicity of Aristolochia bracteata in goats.

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Diarrhea, dyspnea, tympany, arching of the back, loss of condition, and loss of hair from the back were the prominent signs when Aristolochia bracteata was given orally to goats. The main lesions were hemorrhages in the lungs, heart, and kidneys, fatty change and congestion in the liver, mucoid

Fatal renal failure due to the Chinese herb "GuanMu Tong" (Aristolochia manshuriensis): autopsy findings and review of literature.

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Herbal remedies have been used since ancient times and it is now known that they are not completely free of adverse effects. We present the case of a 41-year-old Chinese man, who died in renal failure because he consumed a herbal preparation called "Fen Qing Wu Lin Wan", having GuanMu Tong as main

The combined toxicity of Aristolochia bracteata and Cadaba rotundifolia to goats.

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The sequential development of the clinical signs and lesions in the organs of Nubian goats fed on Aristolochia bracteata (Um Galagel) and Cadaba rotundifolia (Kurmut) and their mixture in certain proportions was studied. Kidney and liver function was tested and the results correlated with

Aristolochic acid and its derivatives as inhibitors of snake venom L-amino acid oxidase.

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Snake venom L-amino acid oxidase (LAAO) exerts toxicity by inducing hemorrhage, pneumorrhagia, pulmonary edema, cardiac edema, liver cell necrosis etc. Being well conserved, inhibitors of the enzyme may be synthesized using the template of the substrate, substrate binding site and features of the

Functional variability of Bothrops atrox venoms from three distinct areas across the Brazilian Amazon and consequences for human envenomings.

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Variability in the composition of snake venoms occurs in different taxa and is usually correlated to snake fitness. Here, we compared B. atrox venoms from three different geographic regions across the Brazilian Amazon and found remarkable functional differences particularly between venoms from two

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