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ascites/phosphatase

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Collection of Data of Ceftobiprole Treated Patients: Comparison of Patients With and Without Certain Diseases

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Rationale and background: Ceftobiprole is a beta-lactam antibiotic with bactericidal activity against a broad spectrum of Gram-positive and Gram-negative bacteria, that was developed to treat patients with pneumonia both in a hospital or community setting. Clinical trials were conducted in adult

A Study to Evaluate Camrelizumab in Combination With Docetaxel +S-1 as Adjuvant Treatment Therapy in Stage III Gastric Cancer

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1. Test population: Patients with stage III gastric cancer confirmed by postoperative pathology 2. Sample size calculation: single arm design was used in this study, and the main outcome was progression free survival. In this study, PD-L1 + CPS ≥ 10% / MSI-H + / EB +, the sample size was estimated

Pirfenidone and Advanced Liver Fibrosis.

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The study will be conducted in compliance with International Standard good clinical practices (GCPs) and the Declaration of Helsinki. The protocol was approved by local Institutional Review Board and registered in clinical trials.gov. Clinical and Laboratory Evaluation Blood counts and liver

The Role of Somatostatin in the Hemodynamics of the Hepatic Circulation in Patients Undergoing Liver Resection

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The purpose of the present clinical trial is to study the effect of somatostatin in the regulation of blood flow of the portal circulation at patients who have undergone hepatectomy. The patients will be randomized in two groups, namely the group that will receive somatostatin (study group) and the

Ursodeoxycholic Acid (UDCA) for Hepatic Sarcoidosis

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Sarcoidosis is a relatively rare, poorly defined autoimmune disease characterized by the formation of sterile granulomas in affected organs, including the liver. The diagnosis of hepatic sarcoid is often presumed based upon an elevated liver-specific isoenzyme of alkaline phosphatase or imaging

Left Lateral Position and Prone Position for Endoscopic Retrograde Cholangiopancreatography

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Methods 1. Written informed consent for the endoscopic retrograde cholangiopancreatography is obtained from all patients. 2. Blood culture is performed, and intravenous 3rd generation cephalosporin is administered routinely. 3. Before endoscopic procedure, patients are randomly assigned to left

Diclophenac Versus Placebo for Pain Control in Diagnostic Colonoscopy

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Aim: To determine the effectiveness of oral diclophenac sodium on the quality of colonoscopy and pain control during diagnostic colonoscopy in hospitalized patients. Hypothesis: Null hypothesis: there is no statistically significant difference between diclophenac sodium and placebo on parameters of

Clinical Evaluation of Anti-CHIKV Hyperimmune Intravenous Immunoglobulins

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The population to be studied will consist of neonates born to mothers presenting with clinical symptoms of Chikungunya within six days before and two days after childbirth. These neonates will therefore be exposed to a high risk of developing a severe form of Chikungunya infection. In most cases the

Efficacy of Switching or Adding Pegylated Interferon in Chronic Hepatitis B Patients on Long Term Oral Antiviral Therapy

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1. HYPOTHESIS AND OBJECTIVES PEG-IFN as an immunomodulatory agent could potentiate the antiviral efficacy of patients on long term nucleos(t)ide analogue therapy and improve early indicators of efficacy, HBeAg loss and reduction in qHBsAg. This study will also test whether add-on compared to switch

Sonoelastography: Ultrasound Method to Measure Liver Fibrosis

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BACKGROUND Chronic liver disease is an important cause of morbidity and mortality in the United States. A retrospective cohort study identified 2,353 patients with newly diagnosed chronic liver disease (63.9 cases/100,000 population). Extrapolating this incidence rate there will be approximately

A Dose Escalation Trial of Radiation Therapy (RT) for Hepatocellular Carcinoma (HCC)

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Synopsis All enrolled patients will receive 3.5 Gy per fraction (five fractions per week) at the following levels; Dose escalation by 7 Gy in 2 fractions to maximum of 63 Gy, as follows: Dose Level I: 3.5 Gy for 12 fractions (42 Gy total) Dose Level II*: 3.5 Gy for 14 fractions (49 Gy total) Dose

Clinical, Inflammatory, and Economic Impact of Dextran 70 in Treating Spontaneous Bacterial Peritonitis

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All patients admitted to the University of Virginia Health system who have clinically or pathologically defined cirrhosis, laboratory evidence consistent with spontaneous bacterial peritonitis and clinically or radiologically accessible ascites will be screened for participation in this

A Pilot Study of Peribulbar Triamcinolone Acetonide for Diabetic Macular Edema

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Diabetic retinopathy is a major cause of visual impairment in the United States. Diabetic macular edema (DME) is a manifestation of diabetic retinopathy that produces loss of central vision. Data from the Wisconsin Epidemiologic Study of Diabetic Retinopathy (WESDR) estimate that after 15 years of

Phase Ⅲ Randomized Trial in Postoperative Hepatocellular Carcinoma

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1. TREATMENT PLAN 1.1 Eligible patients are randomized to receive adjuvant IFN-α for 53 wks or 1.2 Administration of IFN-α 1.21 IFN-α will be started after randomization. 1.22 IFN-α will be administered by subcutaneous injection at the bed time. 1.23 Escalation of IFN-α dosage. 1.231 During the
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