atrial flutter/diarrhée

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Digitalis intoxication; chronic effects manifested by diarrhea and auricular flutter.

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Dronedarone: a new antiarrhythmic agent.

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Dronedarone is an antiarrhythmic agent recently approved by the United States Food and Drug Administration for the reduction of cardiovascular-related hospitalizations in patients with paroxysmal or persistent atrial fibrillation or atrial flutter. The drug is a derivative of amiodarone and has been

Azimilide for atrial fibrillation: clinical trial results and implications.

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Azimilide dihydrochloride (or azimilide) is a class III antiarrhythmic drug currently under investigation that has been tested in atrial fibrillation in four randomized, placebo-controlled clinical trials to assess efficacy and dose range. These investigational trials showed that doses of azimilide

Quinidine-induced hepatotoxicity revisited.

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Although quinidine has been widely used since the beginning of the century, quinidine-induced hepatotoxicity has been recently reported in the literature. We describe a reversible case of quinidine-induced hepatotoxicity. A 62-y-old male with a past medical history of atrial flutter and adult onset

Nadolol for Treatment of Supraventricular Tachycardia in Infants and Young Children.

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Supraventricular tachycardia (SVT) is a common infant arrhythmia, for which beta-blockers are frequently chosen as therapy. Propranolol is a common choice though it is dosed every 6-8 h. We reviewed the clinical results of treating infant SVT with an extemporaneous preparation of nadolol.

[Treatment of atrial fibrillation using intravenous infusion of quinidine].

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Quinidine gluconate was administered slowly by intravenous infusion to 20 patients with atrial fibrillation. Nineteen of them had rheumatic heart disease and the other one had Ebstein's disease. The first ten patients received 0.027 mg/kg/min during 6 hs or less if they returned to normal sinus

Superior mesenteric artery thrombosis after abrupt discontinuation of rivaroxaban.

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We report a case of superior mesenteric artery thrombosis after the abrupt discontinuation of rivaroxaban in a 59-year-old male patient. The initial presentation was of sudden onset abdominal pain, nausea, vomiting, diarrhea, and hematochezia in the setting of recently holding rivaroxaban

Phase I-II study of aclacinomycin for a treatment of acute myeloid leukemia.

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Aclacinomycin A (ACM) was administered for induction treatment to 40 previously treated acute myeloid leukemia (AML) patients. 38 patients aged 2 to 80 years (mean +/- SE, 35.0 +/- 3.2 years) with overt AML were evaluated; of these, seventeen patients were given ACM after an unsuccessful attempt to

[Therapeutic trials of aclarubicin in previously treated acute leukemias and hematosarcomas].

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In a phase I-II trial, 38 patients with acute myeloid leukemia (AML) were given single drug induction therapy with aclarubicin (ACM) according to two dosing schedules: treatment 1: 10 to 30 mg/m2/d to a maximum total dose of 300 mg/m2 or until development of unacceptable toxicity: treatment 2: 15

Phase I-II study of aclarubicin for treatment of acute myeloid leukemia.

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Aclarubicin (ACM) was administered as induction treatment to 40 patients with acute myeloid leukemia (AML) who were either refractory to initial induction chemotherapy or in relapse. Thirty-eight patients with AML, 2-80 years of age (mean +/- SE, 35.0 +/- 3.2), were evaluated during this study.

Probable interaction between warfarin and bee pollen.

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OBJECTIVE A probable interaction between warfarin and honeybee-collected pollen is reported. CONCLUSIONS A 71-year-old Caucasian man arrived at an anticoagulation clinic for routine warfarin monitoring with an International Normalized Ratio (INR) value of 7.1 (therapeutic range, 2.0-3.0). His

The exhausted horse syndrome.

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Exhaustion occurs in most equestrian sports, but it is more frequent in events that require sustained endurance work such as endurance racing, three-day eventing, trial riding, and hunting. Exhaustion is also more likely when an unfit, unacclimatized, or unsound horse is exercised. Mechanisms that

Phase I study of every 2- or 3-week dosing of ramucirumab, a human immunoglobulin G1 monoclonal antibody targeting the vascular endothelial growth factor receptor-2 in patients with advanced solid tumors.

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Ramucirumab is a fully human immunoglobulin G1 monoclonal antibody receptor antagonist designed to block the ligand-binding site of vascular endothelial growth factor receptor-2 (VEGFR-2). An initial phase I study evaluated ramucirumab administered weekly in advanced cancer patients.

Phase I study of every 2- or 3-week dosing of ramucirumab, a human immunoglobulin G1 monoclonal antibody targeting the vascular endothelial growth factor receptor-2 in patients with advanced solid tumors.

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BACKGROUND Ramucirumab is a fully human immunoglobulin G1 monoclonal antibody receptor antagonist designed to block the ligand-binding site of vascular endothelial growth factor receptor-2 (VEGFR-2). An initial phase I study evaluated ramucirumab administered weekly in advanced cancer patients. This

Dronedarone: a new antiarrhythmic agent for the treatment of atrial fibrillation.

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In the armamentarium for rhythm control, amiodarone has been a mainstay of therapy for the management of atrial fibrillation (AF). Although amiodarone has shown to be effective in maintaining sinus rhythm, it has many extracardiac adverse effects. Dronedarone, a benzofuran amiodarone derivative, is

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